Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.38 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TYR | P14679 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31305634 | 0.76 | TRPA1 (0.55) | KDM4EALDH1A1MAPTALOX15SMN1; SMN2 | |
| SCHEMBL2791357 | 0.76 | TRPA1 (0.55) | KDM4EALDH1A1MAPTALOX15SMN1; SMN2 | |
| SCHEMBL6948298 | 0.75 | LMNA (0.43) | ALDH1A1MAPTTSHRTP53LMNA | |
| SCHEMBL6940717 | 0.75 | LMNA (0.43) | ALDH1A1MAPTTSHRTP53LMNA | |
| SCHEMBL6949104 | 0.74 | ALOX5AP (0.47) | MAPTTDP1LMNANFE2L2 | |
| SCHEMBL6940750 | 0.74 | ALOX5AP (0.47) | MAPTTDP1LMNANFE2L2 | |
| SCHEMBL11449785 | 0.73 | ALDH1A1 (0.54) | KDM4EALDH1A1MAPTALOX15SMN1; SMN2 | |
| SCHEMBL10067193 | 0.70 | ALOX15 (0.39) | KDM4EALDH1A1MAPTALOX15SMN1; SMN2 | |
| SCHEMBL11088678 | 0.69 | AKR1C3 (0.48) | CYP1A2TSHRCYP2C9CYP2C19KMT2A | |
| SCHEMBL13378285 | 0.68 | KDM4E (0.50) | KDM4EALDH1A1MAPTALOX15CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |