SCHEMBL6949129

SCHEMBL6949129

OCC1(c2cccc3cc(Br)ccc23)CO1

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.34
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
RXFP1 Q9HBX9 2/20 0.33
MAPT P10636 2/20 0.33
DAO P14920 1/20 0.33
ERN1 O75460 1/20 0.32
SIRT2 Q8IXJ6 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
PNMT P11086 3/20 0.31
PLAU P00749 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11742168 0.81 SLC6A3 (0.42) KMT2AMEN1MAPTKDM4EALDH1A1
SCHEMBL8847372 0.70 POLB (0.43) CYP2A6RXFP1MAPTKDM4EALDH1A1
SCHEMBL11803457 0.67 DAO (0.48) CYP2A6KMT2AMEN1RXFP1MAPT
SCHEMBL6844267 0.67 KDM4E (0.36) KDM4EALDH1A1
SCHEMBL5781832 0.64 CYP2A6 (0.48) CYP2A6KMT2AMEN1RXFP1MAPT
SCHEMBL774118 0.64 PLAU (0.59) CYP2A6KMT2AMEN1RXFP1ERN1
SCHEMBL31716988 0.64 CYP2A6 (0.48) CYP2A6KMT2AMEN1RXFP1MAPT
SCHEMBL30457989 0.64 CYP2A6 (0.52) CYP2A6KMT2AMEN1RXFP1MAPT
SCHEMBL29656897 0.64 CYP2A6 (0.52) CYP2A6KMT2AMEN1RXFP1MAPT
SCHEMBL30366175 0.64 CYP2A6 (0.52) CYP2A6KMT2AMEN1RXFP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1074544-B1 Process for production of 3-(3-pyridyl)-1-propanol derivatives KANEKA CORP (JP) 2003-08-27 EP disclosed
US-6388086-B1 REACTING W 3-METHYLPYRIDINE WITH BASE; THEN EPOXY COMPOUND KANEKA CORPORATION (JP) 2002-05-14 US disclosed
EP-1074544-A1 Process for production of 3-(3-pyridyl)-1-propanol derivatives KANEKA CORPORATION (JP) 2001-02-07 EP disclosed