SCHEMBL6949591

SCHEMBL6949591

N=Nc1ccccc1C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.56
▸ ALOX15 P16050 1/20 0.56
▸ IDE P14735 1/20 0.52
▸ HPGD P15428 2/20 0.48
▸ CA12 O43570 2/20 0.48
▸ CA1 P00915 2/20 0.48
▸ CA2 P00918 2/20 0.48
▸ CA4 P22748 2/20 0.48
▸ CA7 P43166 2/20 0.48
▸ CA9 Q16790 2/20 0.48
▸ KDM4E B2RXH2 1/20 0.48
▸ HMGB1 P09429 1/20 0.48
▸ CA6 P23280 1/20 0.48
▸ SMN1; SMN2 Q16637 1/20 0.48
▸ NAPRT Q6XQN6 1/20 0.48
▸ CA14 Q9ULX7 1/20 0.48
▸ MAPT P10636 4/20 0.46
▸ HDAC8 Q9BY41 1/20 0.46
▸ MYC P01106 1/20 0.46
▸ POLB P06746 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20483047 0.94 ALDH1A1 (0.50) ALDH1A1ALOX15IDEHPGDCA12
Biphenyl-4-Amine SCHEMBL28145149 0.84 HSD17B10 (0.48) ALDH1A1ALOX15IDEHPGDKDM4E
SCHEMBL68503 0.81 IDE (0.71) ALDH1A1ALOX15IDEHPGDCA12
SCHEMBL68504 0.81 IDE (0.71) ALDH1A1ALOX15IDEHPGDCA12
SCHEMBL30822834 0.81 ALDH1A1 (0.52) ALDH1A1ALOX15IDEHPGDCA12
SCHEMBL15273168 0.81 HNF4A (0.49) ALDH1A1ALOX15IDEHPGDCA12
SCHEMBL8424493 0.80 KDM4E (0.39) ALDH1A1ALOX15HPGDCA12CA1
SCHEMBL3056257 0.79 ALDH1A1 (0.59) ALDH1A1ALOX15IDEHPGDCA12
SCHEMBL1081928 0.79 ALDH1A1 (0.59) ALDH1A1ALOX15IDEHPGDCA12
SCHEMBL6888642 0.77 ALDH1A1 (0.56) ALDH1A1ALOX15IDEHPGDCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1261587-B1 STILBENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ANTIVIRAL AGENTS UNIV BASEL (CH) 2003-07-16 — — EP claimed
EP-1261587-A1 STILBENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ANTIVIRAL AGENTS Universität Basel (CH) 2002-12-04 — — EP claimed
WO-2001040194-A1 STILBENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ANTIVIRAL AGENTS UNIVERSITÄT BASEL (CH) 2001-06-07 — — WO claimed
CN-119552371-A Preparation method and application of amphiphilic azo polymer and micelle thereof 辽宁大学 2025-03-04 — — CN disclosed
CN-119552372-A Preparation method of magnetic particle modified amphiphilic polymer 辽宁大学 2025-03-04 — — CN disclosed
US-10711027-B2 DNA polymerase beta inhibitors THE JOHNS HOPKINS UNIVERSITY (US) 2020-07-14 — — US disclosed
US-20190202853-A1 DNA POLYMERASE BETA INHIBITORS THE JOHNS HOPKINS UNIVERSITY 2019-07-04 — — US disclosed
US-9625449-B2 Determining the bioavailability of zinc (II) ions COLGATE-PALMOLIVE COMPANY (US) 2017-04-18 — — US disclosed
EP-2132157-B1 NOVEL CONDENSED RING AROMATIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE HAVING THE SAME CANON KK (JP) 2017-02-01 — — EP disclosed
WO-2016022943-A2 NOVEL MONOMERS FROM BIOMASS NDSU RESEARCH FOUNDATION (US) 2016-02-11 — — WO disclosed
US-8975312-B2 Color indicating epoxy resins and methods thereof 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-03-10 — — US disclosed
EP-0439585-B1 IMMOBILISATION OF LIGANDS BY RADIO-DERIVATIZED POLYMERS MAG GEORG MAYRHOFER & CO OHG (AT) 1997-10-29 — — EP disclosed
US-5196478-A Polystyrene, assays EPIPHARM ALLERGIE-SERVICE GESELLSCHAFT M.B.H. (AT) 1993-03-23 — — US disclosed
EP-0439585-A1 IMMOBILISATION OF LIGANDS BY RADIO-DERIVATIZED POLYMERS. EPIPHARM ALLERGIE SERVICE (AT) 1991-08-07 — — EP disclosed
WO-1991002768-A1 IMMOBILISATION OF LIGANDS BY RADIO-DERIVATIZED POLYMERS EPIPHARM ALLERGIE-SERVICE GESELLSCHAFT M.B.H. (AT) 1991-03-07 — — WO disclosed
EP-0063808-B1 PHOTOGRAPHIC ELEMENTS CONTAINING NONDIFFUSIBLE 6-(2-THIENYLAZO)-3-PYRIDINOL CYAN DYE-RELEASING COMPOUNDS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-09-18 — — EP disclosed
US-4396546-A Photographic products and processes employing novel nondiffusible 6-(2-thienylazo)-3-pyridinol cyan dye-releasing compounds and precursors thereof EASTMAN KODAK COMPANY (US) 1983-08-02 — — US disclosed
US-4385104-A METAL COORDINATION COMPLEX EASTMAN KODAK COMPANY (US) 1983-05-24 — — US disclosed
EP-0063808-A1 Photographic elements containing nondiffusible 6-(2-thienylazo)-3-pyridinol cyan dye-releasing compounds EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1982-11-03 — — EP disclosed
US-4346161-A DIFFUSION TRANSFER EASTMAN KODAK COMPANY (US) 1982-08-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10711027-B2 DNA polymerase beta inhibitors POLB, POLH, POLN ALDH1A1 908/4885ALOX15 3938/4885IDE 1129/4885
US-20190202853-A1 DNA POLYMERASE BETA INHIBITORS POLB, POLH, POLN ALDH1A1 908/4885ALOX15 3938/4885IDE 1129/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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