Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.40 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.40 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | F2R | P25116 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9219963 | 0.81 | GAA (0.54) | TPSAB1TPSD1TPSG1GAASMN1; SMN2 | |
| SCHEMBL3310103 | 0.76 | BRD4 (0.48) | TPSAB1TPSD1TPSG1ITGB3ITGA2B | |
| SCHEMBL7824182 | 0.76 | ALDH1A1 (0.37) | GAASMN1; SMN2ALDH1A1THRBATM | |
| SCHEMBL7824181 | 0.76 | ALDH1A1 (0.37) | GAASMN1; SMN2ALDH1A1THRBATM | |
| SCHEMBL381974 | 0.74 | KDM4E (0.53) | FAAHSMN1; SMN2THRB | |
| SCHEMBL4599331 | 0.73 | ITGB3 (0.49) | ITGB3ITGA2BF2RMEN1KMT2A | |
| SCHEMBL6823133 | 0.73 | SMN1; SMN2 (0.67) | TPSAB1TPSD1TPSG1CHRM4FAAH | |
| SCHEMBL9216792 | 0.73 | GAA (0.51) | ITGB3ITGA2BGAAFAAHSMN1; SMN2 | |
| SCHEMBL9217878 | 0.73 | GAA (0.47) | ITGB3ITGA2BF2RGAAMEN1 | |
| SCHEMBL6948530 | 0.72 | SMN1; SMN2 (0.65) | TPSAB1TPSD1TPSG1CHRM4FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030199541-A1 | Azabicyclic compounds, preparation thereof and use as medicines, in particular as antibacterial agents | ALLERGAN PHARMACEUTICALS INTERNATIONAL LIMITED (IE) | 2003-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199541-A1 | Azabicyclic compounds, preparation thereof and use as medicines, in particular as antibacterial agents | AZI2, NISCH, DCTPP1 | TPSAB1 1951/4885TPSD1 4038/4885TPSG1 4267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.