Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 16/20 | 0.44 |
| ▸ | PYGM | P11217 | 16/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6947787 | 0.92 | PYGM (0.55) | PYGLPYGMNR3C2 | |
| SCHEMBL6952275 | 0.89 | NR3C2 (0.42) | PYGLPYGMNR3C2KDM4EALDH1A1 | |
| SCHEMBL6951169 | 0.87 | NR3C2 (0.43) | PYGLPYGMNR3C2KDM4EALDH1A1 | |
| SCHEMBL6951439 | 0.82 | LMNA (0.44) | PYGLPYGMNR3C2KDM4EALDH1A1 | |
| SCHEMBL5754356 | 0.80 | PYGM (0.51) | PYGLPYGMNR3C2KDM4E | |
| SCHEMBL7307972 | 0.80 | PYGM (0.51) | PYGLPYGMNR3C2KDM4E | |
| SCHEMBL5752638 | 0.80 | PYGM (0.51) | PYGLPYGMNR3C2KDM4E | |
| SCHEMBL6949651 | 0.78 | CYP2C9 (0.53) | KDM4EALDH1A1GAALMNA | |
| SCHEMBL6952771 | 0.77 | NR3C2 (0.42) | PYGLPYGMNR3C2LMNASMN1; SMN2 | |
| SCHEMBL5080218 | 0.77 | PYGL (0.38) | PYGLPYGMNR3C2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657432-B1 | Phenyl-substituted 1,4-dihydropyridines with cerebral activity | BAYER AG (DE) | 2003-03-12 | — | — | EP | claimed |