Sugi Predict

Sugi Predict / Compounds / SCHEMBL69498

SCHEMBL69498

SCHEMBL69498

O=C(CBr)c1cccc(Cl)c1

nearest known ligand 0.61

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ ERCC5 P28715 1/20 0.61
▸ FEN1 P39748 1/20 0.61
▸ GSK3B P49841 5/20 0.59
▸ PTPN1 P18031 4/20 0.57
▸ PARP1 P09874 1/20 0.57
▸ USP2 O75604 1/20 0.46
▸ IDO1 P14902 2/20 0.46
▸ CXCR3 P49682 1/20 0.46
▸ MEN1 O00255 3/20 0.45
▸ KMT2A Q03164 3/20 0.45
▸ NPC1 O15118 1/20 0.45
▸ SMN1; SMN2 Q16637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29419340 1.00 ERCC5 (0.61) ERCC5FEN1GSK3BPTPN1PARP1
SCHEMBL17375912 0.87 ERCC5 (0.56) ERCC5FEN1GSK3BPTPN1PARP1
SCHEMBL9409741 0.85 GSK3B (0.70) GSK3BPTPN1MEN1KMT2ASMN1; SMN2
SCHEMBL4394372 0.85 ERCC5 (0.57) ERCC5FEN1PARP1USP2IDO1
SCHEMBL29962144 0.83 ERCC5 (0.76) ERCC5FEN1PARP1USP2MEN1
SCHEMBL11791699 0.83 ERCC5 (0.76) ERCC5FEN1PARP1USP2MEN1
SCHEMBL4565219 0.82 ERCC5 (0.62) ERCC5FEN1GSK3BPARP1IDO1
SCHEMBL1712221 0.82 ERCC5 (0.62) ERCC5FEN1PARP1IDO1CXCR3
SCHEMBL29621003 0.82 ERCC5 (0.62) ERCC5FEN1GSK3BPARP1IDO1
SCHEMBL97933 0.82 ERCC5 (0.62) ERCC5FEN1GSK3BPARP1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 623 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117088893-A Synthetic method of chalcogen heterobowl-shaped molecular graphene 伊犁师范大学 2023-11-21 — — CN claimed
EP-3958980-B1 TARGETED NOVEL TRIAZOLOTHIADIAZINE DERIVATIVES FOR THE TREATMENT OF LUNG CANCER ANADOLU UNIV (TR) 2023-11-15 — — EP claimed
CN-116003260-B Method for preparing 1-naphthylamine compound from urea derivative and prediction model thereof 广州国家实验室 2023-07-18 — — CN claimed
CN-116003260-A Method for preparing 1-naphthylamine compound from urea derivative and prediction model thereof 广州国家实验室 2023-04-25 — — CN claimed
CN-110092724-B Preparation method of N, N-dimethyl-1-naphthylamine compound 湖南大学 2021-08-31 — — CN claimed
CN-110305048-A One kind preparing α-sulfuryl ketone compounds synthetic method by α, α-two bromo ketone one kettle way 温州大学 2019-10-08 — — CN claimed
CN-110092724-A A kind of preparation method of N, N- dimethyl-1-naphthylamine class compound 湖南大学 2019-08-06 — — CN claimed
US-20140235863-A1 SUBSTITUTED 4-ARYLTHIAZOLES AND PROCESS OF PREPARATION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2014-08-21 — — US claimed
WO-2012164572-A1 SUBSTITUTED 4-ARYLTHIAZOLES AND PROCESS OF PREPARATION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2012-12-06 — — WO claimed
CN-101333157-A Method for synthesizing 2,3'-dichloroacetophenone XUZHOU NUOTE CHEMICALS CO LTD (CN) 2008-12-31 — — CN claimed
JP-9002986-A — — None — — JP disclosed
US-20250388582-A1 NOVEL BICYCLIC HETEROARYL COMPOUND AND USE THEREOF ILDONG PHARMACEUTICAL CO LTD (KR) 2025-12-25 — — US disclosed
US-20250215029-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. 2025-07-03 — — US disclosed
EP-4556476-A1 NOVEL BICYCLIC HETEROARYL COMPOUND AND USE THEREOF Ildong Pharmaceutical Co., Ltd. (KR) 2025-05-21 — — EP disclosed
US-20250136581-A1 SUBSTITUTED TRIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF SHANGHAI SIMRD BIOTECHNOLOGY CO., LTD. (CN) 2025-05-01 — — US disclosed
US-4124602-A OPTIONALLY SUBSTITUTED 3-(CYANOPHENYL)BENZOFURANS RIKER LABORATORIES, INC. (US) 1978-11-07 — — US disclosed
US-4054719-A ACRYLIC ESTER, TERTIARY AMINE AMERICAN CYANAMID COMPANY (US) 1977-10-18 — — US disclosed
US-4048323-A Antimicrobial (2-nitro-3-benzofuranyl)-benzoic acids RIKER LABORATORIES, INC. (US) 1977-09-13 — — US disclosed
US-4033978-A Thiacycl[2.2.2]azine carboxylic acids SYNTEX (U.S.A.) INC. (US) 1977-07-05 — — US disclosed
US-3965181-A Tricyclic pharmacological agents, intermediates and methods of making SYNTEX (U.S.A.) INC. (US) 1976-06-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140235863-A1 SUBSTITUTED 4-ARYLTHIAZOLES AND PROCESS OF PREPARATION THEREOF TST, NQO1, FNTB ERCC5 4362/4885FEN1 3952/4885GSK3B 3349/4885
US-20250215029-A1 STAT MODULATORS AND USES THEREOF STAT6, STAT3, STAT5A ERCC5 4879/4885FEN1 4852/4885GSK3B 674/4885
US-20250388582-A1 NOVEL BICYCLIC HETEROARYL COMPOUND AND USE THEREOF GBA1, PIKFYVE, MAN2B1 ERCC5 3142/4885FEN1 3309/4885GSK3B 3174/4885
US-20250136581-A1 SUBSTITUTED TRIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF GABRA5, SLC6A11, GABRA1 ERCC5 3516/4885FEN1 4380/4885GSK3B 393/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.