Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | BCL6 | P41182 | 1/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8885589 | 0.82 | ALDH1A1 (0.61) | RAB9ANPC1MAOAMAOBSMN1; SMN2 | |
| SCHEMBL525241 | 0.81 | NPC1 (0.60) | RAB9ANPC1HIF1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10085259 | 0.80 | RAB9A (0.52) | RAB9ANPC1MAOAMAOBSMN1; SMN2 | |
| SCHEMBL8891430 | 0.79 | KMT2A (0.63) | RAB9ANPC1MAOAMAOBSMN1; SMN2 | |
| SCHEMBL29355425 | 0.79 | RAB9A (0.51) | RAB9ANPC1MAOAMAOBSMN1; SMN2 | |
| SCHEMBL6962348 | 0.79 | RAB9A (0.51) | RAB9ANPC1MAOAMAOBROCK2 | |
| SCHEMBL29355888 | 0.79 | RAB9A (0.51) | RAB9ANPC1MAOAMAOBSMN1; SMN2 | |
| SCHEMBL8683376 | 0.78 | ROCK1 (0.75) | RAB9ANPC1ROCK2ROCK1SMN1; SMN2 | |
| SCHEMBL6962738 | 0.77 | ALDH1A1 (0.70) | RAB9ANPC1ROCK2ROCK1SMN1; SMN2 | |
| SCHEMBL6880276 | 0.76 | ROCK2 (0.65) | ROCK2ROCK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540143-B1 | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 2003-02-05 | — | — | EP | disclosed |
| US-5658907-A | THIOUREA VIRICIDES | MEDIVIR A/B (SE) | 1997-08-19 | — | — | US | disclosed |
| US-5593993-A | VIRICIDES FOR HTLV TREATMENT OF AIDS | MEDIVIR AB (SE) | 1997-01-14 | — | — | US | disclosed |