SCHEMBL10085259

SCHEMBL10085259

CCc1csc(NC(=S)NCCc2ccccc2)n1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 8/20 0.52
NPC1 O15118 4/20 0.52
MAOA P21397 1/20 0.52
MAOB P27338 1/20 0.52
ALDH1A1 P00352 6/20 0.52
LMNA P02545 4/20 0.52
KDM4E B2RXH2 2/20 0.52
SMN1; SMN2 Q16637 6/20 0.51
MAPK1 P28482 4/20 0.51
ALOX12 P18054 3/20 0.50
GAA P10253 3/20 0.50
CYP1A2 P05177 2/20 0.50
CYP3A4 P08684 2/20 0.50
CYP2D6 P10635 2/20 0.50
CYP2C19 P33261 2/20 0.50
HPGD P15428 1/20 0.50
MAPT P10636 4/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
KMT2A Q03164 3/20 0.48
PKM P14618 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29355888 0.91 RAB9A (0.51) RAB9ANPC1MAOAMAOBALDH1A1
SCHEMBL10082522 0.87 SMN1; SMN2 (0.53) RAB9AMAOAMAOBALDH1A1KDM4E
SCHEMBL91393 0.85 ROCK2 (0.64) RAB9ANPC1LMNASMN1; SMN2MAPT
SCHEMBL8885589 0.85 ALDH1A1 (0.61) RAB9ANPC1MAOAMAOBALDH1A1
SCHEMBL29355425 0.81 RAB9A (0.51) RAB9ANPC1MAOAMAOBALDH1A1
SCHEMBL8891430 0.81 KMT2A (0.63) RAB9ANPC1MAOAMAOBALDH1A1
SCHEMBL6950085 0.80 RAB9A (0.52) RAB9ANPC1MAOAMAOBALDH1A1
SCHEMBL6962348 0.79 RAB9A (0.51) RAB9ANPC1MAOAMAOBALDH1A1
SCHEMBL8683376 0.78 ROCK1 (0.75) RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2
SCHEMBL10084284 0.77 MEN1 (0.67) RAB9ANPC1MAOBALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240251654-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2024-07-25 US claimed
EP-4694175-A1 IMAGING DEVICE Sony Semiconductor Solutions Corporation (JP) 2026-02-11 EP disclosed
WO-2024202331-A1 IMAGING DEVICE ソニーセミコンダクタソリューションズ株式会社 2024-10-03 WO disclosed
WO-2024204072-A1 IMAGING DEVICE ソニーセミコンダクタソリューションズ株式会社 2024-10-03 WO disclosed
US-11418789-B2 Content adaptive quantization for video coding INTEL CORPORATION (US) 2022-08-16 US disclosed
US-11230599-B2 Tumor mutational load MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2022-01-25 US disclosed
US-8119645-B2 Fungicide hydroximoyl-tetrazole derivatives BAYER CROPSCIENCE AG (DE) 2012-02-21 US disclosed
US-20090291969-A1 Fungicide hydroximoyl-tetrazole derivatives BAYER CROPSCIENCE AG (DE) 2009-11-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240251654-A1 ORGANIC ELECTROLUMINESCENT DEVICE LEF1, EFNA1, EML4 RAB9A 2013/4885NPC1 2452/4885MAOA 1886/4885
US-20090291969-A1 Fungicide hydroximoyl-tetrazole derivatives HAAO, HAO1, CYP51A1 RAB9A 3411/4885NPC1 3836/4885MAOA 1186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.