SCHEMBL6950130

SCHEMBL6950130

Cc1cc([C@@H](CCO)OC(N)=O)ccc1OC(=O)N(C)C

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NCEH1 Q6PIU2 3/20 0.39
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6948132 0.81 RAB9A (0.51) ALDH1A1
SCHEMBL5199748 0.81 RAB9A (0.51) ALDH1A1
SCHEMBL5199107 0.80 ACHE (0.55)
SCHEMBL3865720 0.78 NCEH1 (0.41) NCEH1ALDH1A1
SCHEMBL3865739 0.78 NCEH1 (0.41) NCEH1ALDH1A1
SCHEMBL5199111 0.77 NCEH1 (0.40) NCEH1
SCHEMBL6950959 0.76 RAB9A (0.42) NCEH1ALDH1A1
SCHEMBL6950962 0.76 NCEH1 (0.40) NCEH1
SCHEMBL6950134 0.74 TSHR (0.47) ALDH1A1
SCHEMBL18883617 0.70 NCEH1 (0.44) NCEH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1362844-A1 BENZYLAMINE ANALOGUE Sankyo Company, Limited (JP) 2003-11-19 EP disclosed