SCHEMBL6950962

SCHEMBL6950962

Cc1c(OC(=O)N(C)C)cccc1C(CCO)OC(N)=O

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NCEH1 Q6PIU2 5/20 0.40
BCHE P06276 1/20 0.37
ACHE P22303 6/20 0.36
TSHR P16473 2/20 0.35
PKM P14618 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5199111 0.89 NCEH1 (0.40) NCEH1BCHEACHETSHRPKM
SCHEMBL6950134 0.83 TSHR (0.47) ACHETSHR
SCHEMBL3865832 0.78 NCEH1 (0.42) NCEH1BCHEACHETSHRPKM
SCHEMBL6950130 0.76 NCEH1 (0.39) NCEH1
SCHEMBL6950959 0.76 RAB9A (0.42) NCEH1BCHEACHEPKM
SCHEMBL5199107 0.75 ACHE (0.55) BCHEACHE
SCHEMBL3871280 0.74 NCEH1 (0.38) NCEH1BCHEACHETSHR
SCHEMBL5199748 0.74 RAB9A (0.51) BCHEACHEPKM
SCHEMBL6948132 0.74 RAB9A (0.51) BCHEACHEPKM
SCHEMBL5199102 0.72 CYP1A2 (0.40) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1362844-A1 BENZYLAMINE ANALOGUE Sankyo Company, Limited (JP) 2003-11-19 EP disclosed