Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6948132 | 1.00 | RAB9A (0.51) | RAB9AKMT2AGAAALDH1A1PKM | |
| SCHEMBL5199107 | 0.85 | ACHE (0.55) | BCHEACHE | |
| SCHEMBL22813671 | 0.81 | ADRB1 (0.54) | ADRB1HTR2AHTR2BSIGMAR1 | |
| SCHEMBL6950959 | 0.81 | RAB9A (0.42) | RAB9AKMT2AGAAALDH1A1PKM | |
| SCHEMBL6950130 | 0.81 | NCEH1 (0.39) | ALDH1A1 | |
| SCHEMBL5199111 | 0.76 | NCEH1 (0.40) | RAB9APKMBCHEACHE | |
| SCHEMBL22813473 | 0.75 | ADRB1 (0.49) | PKMNPSR1ADRB1HTR2AHTR2B | |
| SCHEMBL28552915 | 0.75 | ADRB1 (0.49) | PKMNPSR1ADRB1HTR2AHTR2B | |
| SCHEMBL6950634 | 0.74 | RAB9A (0.53) | RAB9AKMT2AGAAALDH1A1PKM | |
| SCHEMBL6950962 | 0.74 | NCEH1 (0.40) | PKMBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362844-B1 | BENZYLAMINE ANALOGUE | BTG INT LTD (GB) | 2007-12-05 | — | — | EP | disclosed |