Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | BUB1 | O43683 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6942893 | 0.87 | NAMPT (0.40) | LMNAACHESMPD3ALDH1A1POLB | |
| SCHEMBL6950893 | 0.87 | GAA (0.47) | ALDH1A1GAAMAPT | |
| SCHEMBL6947210 | 0.81 | NTRK3 (0.47) | BUB1LMNASMN1; SMN2 | |
| SCHEMBL6948327 | 0.68 | HSD17B10 (0.54) | LMNASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL6948393 | 0.67 | MAPT (0.46) | LMNASMN1; SMN2ALDH1A1GAAPOLB | |
| SCHEMBL6948428 | 0.67 | FAAH (0.47) | LMNASMN1; SMN2ALDH1A1POLBMAPT | |
| SCHEMBL6777504 | 0.65 | TYK2 (0.43) | BUB1LMNASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL6947652 | 0.64 | HTR2A (0.34) | ALDH1A1 | |
| SCHEMBL10013879 | 0.63 | ALDH1A1 (0.47) | ALDH1A1MAPT | |
| SCHEMBL351647 | 0.63 | ALDH1A1 (0.47) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1030838-B1 | METHOD OF SYNTHESIS OF PYRROLE AMIDES | PFIZER PROD INC (US) | 2003-01-22 | — | — | EP | claimed |