Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 6/20 | 0.60 |
| ▸ | MMP3 | P08254 | 5/20 | 0.60 |
| ▸ | MMP1 | P03956 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 4/20 | 0.43 |
| ▸ | MMP8 | P22894 | 4/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.43 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.43 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.43 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.43 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.43 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.43 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.43 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.43 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.43 |
| ▸ | PSMA5 | P28066 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6951429 | 0.88 | MMP3 (0.46) | MMP9MMP3MMP1MEN1KMT2A | |
| SCHEMBL6944864 | 0.87 | MMP3 (0.46) | MMP9MMP3MMP1MMP2 | |
| SCHEMBL6947712 | 0.85 | MMP1 (0.55) | MMP9MMP3MMP1MMP2MMP8 | |
| SCHEMBL6956115 | 0.84 | MMP3 (0.44) | MMP9MMP3MMP1MEN1KMT2A | |
| SCHEMBL6952213 | 0.83 | KDM4E (0.43) | MMP9MMP3MMP1KMT2AKDM4E | |
| SCHEMBL7452724 | 0.82 | MMP1 (0.48) | MMP9MMP3MMP1MMP2 | |
| SCHEMBL6948615 | 0.82 | MMP1 (0.48) | MMP9MMP3MMP1MMP2 | |
| SCHEMBL6956564 | 0.82 | KDM4E (0.43) | MMP9MMP3MMP1MEN1KMT2A | |
| SCHEMBL6950920 | 0.81 | MMP3 (0.47) | MMP9MMP3MMP1MMP2 | |
| SCHEMBL6953482 | 0.80 | ALDH1A1 (0.49) | MMP9MMP3MMP1MMP2MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824544-B1 | PEPTIDYL COMPOUNDS WHICH INHIBIT METALLOPROTEINASE AND TNF LIBERATION AND THEIR THERAPEUTIC USE | DARWIN DISCOVERY LTD (GB) | 2003-04-16 | — | — | EP | claimed |
| EP-0824544-B1 | PEPTIDYL COMPOUNDS WHICH INHIBIT METALLOPROTEINASE AND TNF LIBERATION AND THEIR THERAPEUTIC USE | DARWIN DISCOVERY LTD (GB) | 2003-04-16 | — | — | EP | disclosed |
| US-5994293-A | Peptidyl compounds and their therapeutic use | DARWIN DISCOVERY LTD. (GB) | 1999-11-30 | — | — | US | disclosed |