Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955388 | 0.85 | MAPK1 (0.61) | RAB9AMAPK1HTTLMNANPSR1 | |
| SCHEMBL6952404 | 0.79 | TNF (0.46) | TNFRAB9ARXFP1HTTPPARG | |
| SCHEMBL6947078 | 0.79 | SMN1; SMN2 (0.63) | RAB9AMAPK1LMNAKMT2AMEN1 | |
| SCHEMBL6957101 | 0.79 | L3MBTL1 (0.45) | RAB9AMAPK1PPARGLMNAALDH1A1 | |
| SCHEMBL6956124 | 0.78 | ACKR3 (0.50) | MAPK1KDM4EHTTPPARGLMNA | |
| SCHEMBL6948727 | 0.74 | PPARG (0.56) | TNFRAB9APPARGPPARDPPARA | |
| SCHEMBL6950736 | 0.73 | DRD3 (0.39) | PPARGKMT2AMEN1PPARA | |
| SCHEMBL6957273 | 0.73 | PPARG (0.47) | TNFRAB9AMAPK1KDM4ERXFP1 | |
| SCHEMBL6952907 | 0.73 | TP53 (0.40) | PPARGLMNANPSR1KMT2AMEN1 | |
| SCHEMBL6949189 | 0.73 | MAPK1 (0.57) | RAB9AMAPK1HTTLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |