Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | MMP13 | P45452 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6950736 | 0.83 | DRD3 (0.39) | PPARALTA4HMEN1KMT2APPARG | |
| SCHEMBL8306718 | 0.76 | NPC1 (0.41) | MAPTPPARALTA4HMEN1KMT2A | |
| SCHEMBL6952000 | 0.74 | ITGB3 (0.41) | PPARAPPARG | |
| SCHEMBL6957101 | 0.73 | L3MBTL1 (0.45) | TP53MAPTLMNAPPARAPPARG | |
| SCHEMBL6955185 | 0.73 | LTA4H (0.37) | MAPTPPARALTA4HMEN1KMT2A | |
| SCHEMBL6952249 | 0.73 | PPARG (0.39) | PPARAKMT2APPARG | |
| SCHEMBL6950757 | 0.73 | TNF (0.45) | MAPTLMNAPPARAMEN1KMT2A | |
| SCHEMBL6955245 | 0.72 | PPARG (0.40) | TP53MAPTLMNAPPARAPPARG | |
| SCHEMBL6953968 | 0.72 | PPARG (0.35) | TP53MAPTLMNAPPARALTA4H | |
| SCHEMBL6952404 | 0.72 | TNF (0.46) | TP53MAPTPPARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |