Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | MARK3 | P27448 | 1/20 | 0.32 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.32 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6950815 | 1.00 | BCHE (0.32) | BCHEPIM1MARK3MAP4K2CAMK2B | |
| SCHEMBL27677795 | 0.85 | CHRM5 (0.36) | GPR119 | |
| SCHEMBL16060936 | 0.78 | PIM1 (0.36) | BCHEPIM1MARK3MAP4K2CAMK2B | |
| SCHEMBL6555080 | 0.77 | PIM1 (0.35) | BCHEPIM1MARK3MAP4K2CAMK2B | |
| SCHEMBL4149607 | 0.77 | PIM1 (0.37) | BCHEPIM1MARK3MAP4K2CAMK2B | |
| SCHEMBL20864185 | 0.76 | FAAH (0.43) | BCHEPIM1MARK3MAP4K2CAMK2B | |
| SCHEMBL9235001 | 0.75 | PIM1 (0.35) | BCHEPIM1MARK3MAP4K2CAMK2B | |
| SCHEMBL2789678 | 0.75 | NR1H2 (0.38) | BCHEPIM1MARK3MAP4K2CAMK2B | |
| SCHEMBL8312657 | 0.74 | GPR119 (0.36) | BCHEPIM1MARK3MAP4K2CAMK2B | |
| SCHEMBL15874826 | 0.72 | TBXAS1 (0.46) | PIM1MARK3MAP4K2CAMK2BPIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757677-B1 | BENZOCYCLOHEXYLIMIDAZOLETHIONE DERIVATIVES | SYNTEX LLC (US) | 2003-06-18 | — | — | EP | disclosed |