Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.36 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6580005 | 0.87 | SLC6A4 (0.41) | LMNASLC6A4SLC7A5SLC6A2CYP1A2 | |
| SCHEMBL6951984 | 0.82 | SLC7A5 (0.41) | LMNASLC6A4SLC7A5SLC6A2CYP1A2 | |
| SCHEMBL4793873 | 0.79 | — | — | |
| SCHEMBL20703823 | 0.78 | MCHR1 (0.33) | — | |
| SCHEMBL8678808 | 0.77 | L3MBTL1 (0.33) | LMNASLC6A4SLC6A2CYP1A2CYP2D6 | |
| SCHEMBL4896034 | 0.77 | ADRA2A (0.40) | IGLV6-57SLC6A4ADRA2B | |
| SCHEMBL440263 | 0.77 | MCHR1 (0.34) | TSHRALDH1A1 | |
| SCHEMBL7471512 | 0.76 | SRD5A2 (0.36) | LMNASLC6A4SLC6A2CYP1A2CYP2D6 | |
| SCHEMBL8746389 | 0.75 | PPARG (0.38) | LMNASLC6A4SLC6A2CYP3A4CYP2D6 | |
| SCHEMBL11149147 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322816-A1 | PYRAZOLE BORONIC ACID COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USES THEREOF | BEIJING SONGRUN PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2023-10-12 | — | — | US | claimed |
| CN-114075227-B | Pyrazole boric acid compound, pharmaceutical composition containing pyrazole boric acid compound and application of pyrazole boric acid compound and pharmaceutical composition | 北京嵩润医药科技有限责任公司 | 2023-07-04 | — | — | CN | claimed |
| EP-4201941-A1 | PYRAZOLE BORONIC ACID COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USES THEREOF | Beijing Songrun Pharmaceutical Technology Co., Ltd. (CN) | 2023-06-28 | — | — | EP | claimed |
| CN-114075227-A | Pyrazole boronic acid compounds, pharmaceutical compositions comprising the same and uses thereof | 北京大学 | 2022-02-22 | — | — | CN | claimed |
| US-20230322816-A1 | PYRAZOLE BORONIC ACID COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USES THEREOF | BEIJING SONGRUN PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2023-10-12 | — | — | US | disclosed |
| CN-114075227-B | Pyrazole boric acid compound, pharmaceutical composition containing pyrazole boric acid compound and application of pyrazole boric acid compound and pharmaceutical composition | 北京嵩润医药科技有限责任公司 | 2023-07-04 | — | — | CN | disclosed |
| EP-4201941-A1 | PYRAZOLE BORONIC ACID COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USES THEREOF | Beijing Songrun Pharmaceutical Technology Co., Ltd. (CN) | 2023-06-28 | — | — | EP | disclosed |
| CN-114075227-A | Pyrazole boronic acid compounds, pharmaceutical compositions comprising the same and uses thereof | 北京大学 | 2022-02-22 | — | — | CN | disclosed |
| EP-0711762-B1 | PROCESS FOR PRODUCING TETRAZOLE COMPOUNDS | SUMITOMO CHEMICAL CO (JP) | 2003-08-06 | — | — | EP | disclosed |
| US-6277998-B1 | REACTING 2-CYANO-4-OXO-4H-BENZOPYRAN COMPOUND WITH HYDROGEN SULFIDE AND THEN REACTING PROUDCT WITH ALKYL HALIDE; REACTING THE PRODUCT WITH HYDRAZINE OR ITS SALT AND THEN WITH NITROUS ACID COMPOUND TO OBTAIN TETRAZOLE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-08-21 | — | — | US | disclosed |
| US-6191289-B1 | REACTING A 4-OXO-4H-BENZOPYRAN GROUP SUBSTITUTED WITH AMIDE OR A PHENYL GROUP IN ITS 2 POSITION IS REACTED WITH ANHYDROUS HYDRAZINE OR SALT IN PRESENCE OF CATALYST FOLLOWED BY REACTING WITH NITROUS ACID OR SALT TO FORM TETRAZOLE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-02-20 | — | — | US | disclosed |
| US-5874593-A | SULFUR CONTAINING AMIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-02-23 | — | — | US | disclosed |
| US-5635508-A | FUNGICIDES | NOVARTIS AG (CH) | 1997-06-03 | — | — | US | disclosed |
| EP-0711762-A1 | PROCESS FOR PRODUCING TETRAZOLE COMPOUND AND INTERMEDIATE THEREFOR | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-05-15 | — | — | EP | disclosed |
| US-5453427-A | Control phytopathogenic fungi especially in monocotelydons, podery mildew and rust | SANDOZ LTD. (CH) | 1995-09-26 | — | — | US | disclosed |
| EP-0634405-A1 | Pyrimidinyl acrylic acid derivatives, process for their preparation and their use for the control of phytopathogens | SANDOZ LTD. (CH) | 1995-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322816-A1 | PYRAZOLE BORONIC ACID COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USES THEREOF | PSMB11, PSMB7, PSMC5 | IGLV6-57 3489/4885LMNA 3364/4885SLC6A4 4486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.