Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.34 |
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.33 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14648029 | 0.86 | SLC6A4 (0.34) | SLC6A4 | |
| SCHEMBL14648169 | 0.86 | ADRB2 (0.37) | ADRA2ARORCHTR6SLC6A4 | |
| SCHEMBL3326062 | 0.81 | SRC (0.30) | — | |
| SCHEMBL10497076 | 0.81 | CES2 (0.32) | TAAR1 | |
| SCHEMBL7471512 | 0.80 | SRD5A2 (0.36) | ADRA2AADRA2BHTR6SLC6A4 | |
| SCHEMBL3140126 | 0.80 | — | — | |
| SCHEMBL7590298 | 0.80 | UGT2B7 (0.46) | ADRA2AADRA2BADRA2CSLC6A4 | |
| SCHEMBL14647918 | 0.80 | PDE2A (0.41) | SLC6A4 | |
| SCHEMBL130062 | 0.79 | KMT2A (0.34) | — | |
| SCHEMBL11401037 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322816-A1 | PYRAZOLE BORONIC ACID COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USES THEREOF | BEIJING SONGRUN PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2023-10-12 | — | — | US | claimed |
| CN-114075227-B | Pyrazole boric acid compound, pharmaceutical composition containing pyrazole boric acid compound and application of pyrazole boric acid compound and pharmaceutical composition | 北京嵩润医药科技有限责任公司 | 2023-07-04 | — | — | CN | claimed |
| EP-4201941-A1 | PYRAZOLE BORONIC ACID COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USES THEREOF | Beijing Songrun Pharmaceutical Technology Co., Ltd. (CN) | 2023-06-28 | — | — | EP | claimed |
| CN-114075227-A | Pyrazole boronic acid compounds, pharmaceutical compositions comprising the same and uses thereof | 北京大学 | 2022-02-22 | — | — | CN | claimed |
| CN-107074788-A | Substituted heterocyclic derivatives, preparation method and application thereof | 厦门大学 | 2017-08-18 | — | — | CN | claimed |
| US-20080312271-A1 | AZABENZIMIDAZOLYL COMPOUNDS | PFIZER INC. | 2008-12-18 | — | — | US | claimed |
| US-20080280933-A1 | BENZIMIDAZOLYL COMPOUNDS | EFREMOV IVAN | 2008-11-13 | — | — | US | claimed |
| EP-1351946-A2 | MATERIALS AND METHODS TO POTENTIATE CANCER TREATMENT | ICOS CORPORATION (US) | 2003-10-15 | — | — | EP | claimed |
| US-20020165218-A1 | Materials and methods to potentiate cancer treatment | LUITPOLD PHARMACEUTICALS, INC. | 2002-11-07 | — | — | US | claimed |
| WO-2002020500-A2 | MATERIALS AND METHODS TO POTENTIATE CANCER TREATMENT | ICOS CORPORATION (US) | 2002-03-14 | — | — | WO | claimed |
| US-20230322816-A1 | PYRAZOLE BORONIC ACID COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USES THEREOF | BEIJING SONGRUN PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2023-10-12 | — | — | US | disclosed |
| CN-114075227-B | Pyrazole boric acid compound, pharmaceutical composition containing pyrazole boric acid compound and application of pyrazole boric acid compound and pharmaceutical composition | 北京嵩润医药科技有限责任公司 | 2023-07-04 | — | — | CN | disclosed |
| EP-4201941-A1 | PYRAZOLE BORONIC ACID COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USES THEREOF | Beijing Songrun Pharmaceutical Technology Co., Ltd. (CN) | 2023-06-28 | — | — | EP | disclosed |
| CN-114075227-A | Pyrazole boronic acid compounds, pharmaceutical compositions comprising the same and uses thereof | 北京大学 | 2022-02-22 | — | — | CN | disclosed |
| CN-107074788-A | Substituted heterocyclic derivatives, preparation method and application thereof | 厦门大学 | 2017-08-18 | — | — | CN | disclosed |
| EP-0468470-B1 | Benzimidazoles, medicaments containing them and process for their preparation | THOMAE GMBH DR K (DE) | 1997-04-16 | — | — | EP | disclosed |
| EP-0711762-A1 | PROCESS FOR PRODUCING TETRAZOLE COMPOUND AND INTERMEDIATE THEREFOR | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-05-15 | — | — | EP | disclosed |
| US-5453427-A | Control phytopathogenic fungi especially in monocotelydons, podery mildew and rust | SANDOZ LTD. (CH) | 1995-09-26 | — | — | US | disclosed |
| EP-0634405-A1 | Pyrimidinyl acrylic acid derivatives, process for their preparation and their use for the control of phytopathogens | SANDOZ LTD. (CH) | 1995-01-18 | — | — | EP | disclosed |
| US-4613611-A | HYPOGLYCEMIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1986-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280933-A1 | BENZIMIDAZOLYL COMPOUNDS | PAICS, TMBIM6, ABCG2 | ADRA2A 1209/4885ADRA2B 815/4885ADRA2C 238/4885 |
| US-20080312271-A1 | AZABENZIMIDAZOLYL COMPOUNDS | AZI2, PAICS, UGT2B7 | ADRA2A 936/4885ADRA2B 280/4885ADRA2C 159/4885 |
| US-20230322816-A1 | PYRAZOLE BORONIC ACID COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USES THEREOF | PSMB11, PSMB7, PSMC5 | ADRA2A 3038/4885ADRA2B 1931/4885ADRA2C 2525/4885 |
| US-20020165218-A1 | Materials and methods to potentiate cancer treatment | DCK, CHEK2, CHEK1 | ADRA2A 4205/4885ADRA2B 4042/4885ADRA2C 3732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.