Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 3/20 | 0.41 |
| ▸ | SLC9A5 | Q14940 | 1/20 | 0.41 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 14/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 12/20 | 0.33 |
| ▸ | USP9X | Q93008 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6948994 | 0.79 | SLC9A1 (0.33) | SLC9A1SLC9A5SLC9A2MTNR1BMTNR1A | |
| SCHEMBL25108307 | 0.70 | USP9X (0.43) | SLC9A1SLC9A5SLC9A2MTNR1BMTNR1A | |
| SCHEMBL1286533 | 0.69 | SLC9A1 (0.36) | SLC9A1SLC9A5SLC9A2MTNR1BMTNR1A | |
| SCHEMBL20889391 | 0.68 | SLC9A1 (0.39) | SLC9A1SLC9A5SLC9A2MTNR1BMTNR1A | |
| SCHEMBL19682593 | 0.68 | SLC9A1 (0.39) | SLC9A1SLC9A5SLC9A2MTNR1BMTNR1A | |
| SCHEMBL6950801 | 0.68 | PARP1 (0.32) | — | |
| SCHEMBL21626216 | 0.67 | MTNR1B (0.47) | SLC9A1SLC9A5SLC9A2MTNR1BMTNR1A | |
| SCHEMBL28000875 | 0.66 | SLC9A1 (0.40) | SLC9A1SLC9A5SLC9A2MTNR1BMTNR1A | |
| SCHEMBL19690337 | 0.66 | MTNR1B (0.39) | SLC9A1SLC9A5SLC9A2MTNR1BMTNR1A | |
| SCHEMBL19690338 | 0.66 | MTNR1B (0.39) | SLC9A1SLC9A5SLC9A2MTNR1BMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901483-B1 | BENZOFURANS AND BENZOPYRANS AS CHRONOBIOLOGICAL AGENTS | GLAXO GROUP LTD (GB) | 2003-07-09 | — | — | EP | claimed |
| US-5981572-A | Benzofurans and benzopyrans as chronobiological agents | GLAXO WELLCOME INC. (US) | 1999-11-09 | — | — | US | claimed |
| EP-0901483-A2 | BENZOFURANS AND BENZOPYRANS AS CHRONOBIOLOGICAL AGENTS | GLAXO GROUP LIMITED (GB) | 1999-03-17 | — | — | EP | claimed |
| WO-1997043272-A2 | BENZOFURANS AND BENZOPYRANS AS CHRONOBIOLOGICAL AGENTS | GLAXO GROUP LIMITED (GB) | 1997-11-20 | — | — | WO | claimed |
| EP-0901483-B1 | BENZOFURANS AND BENZOPYRANS AS CHRONOBIOLOGICAL AGENTS | GLAXO GROUP LTD (GB) | 2003-07-09 | — | — | EP | disclosed |
| US-5981572-A | Benzofurans and benzopyrans as chronobiological agents | GLAXO WELLCOME INC. (US) | 1999-11-09 | — | — | US | disclosed |
| EP-0901483-A2 | BENZOFURANS AND BENZOPYRANS AS CHRONOBIOLOGICAL AGENTS | GLAXO GROUP LIMITED (GB) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997043272-A2 | BENZOFURANS AND BENZOPYRANS AS CHRONOBIOLOGICAL AGENTS | GLAXO GROUP LIMITED (GB) | 1997-11-20 | — | — | WO | disclosed |