Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 2/20 | 0.36 |
| ▸ | SLC9A5 | Q14940 | 1/20 | 0.35 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 17/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 16/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1286539 | 0.83 | SLC9A1 (0.38) | SLC9A1SLC9A5SLC9A2MTNR1BMTNR1A | |
| SCHEMBL1286554 | 0.72 | SLC9A1 (0.36) | SLC9A1SLC9A5SLC9A2MTNR1BMTNR1A | |
| SCHEMBL6950866 | 0.69 | SLC9A1 (0.41) | SLC9A1SLC9A5SLC9A2MTNR1BMTNR1A | |
| SCHEMBL8484812 | 0.69 | SLC9A1 (0.42) | SLC9A1SLC9A5SLC9A2MTNR1BMTNR1A | |
| SCHEMBL1286493 | 0.66 | MTNR1B (0.37) | SLC9A1SLC9A5SLC9A2MTNR1BMTNR1A | |
| SCHEMBL1286505 | 0.66 | MTNR1B (0.37) | SLC9A1SLC9A5SLC9A2MTNR1BMTNR1A | |
| SCHEMBL1286496 | 0.66 | SLC9A1 (0.38) | SLC9A1SLC9A5SLC9A2MTNR1BMTNR1A | |
| SCHEMBL6508980 | 0.65 | KMT2A (0.48) | — | |
| SCHEMBL1286528 | 0.65 | MTNR1B (0.37) | SLC9A1SLC9A5SLC9A2MTNR1BMTNR1A | |
| SCHEMBL1286510 | 0.65 | SLC9A1 (0.43) | SLC9A1SLC9A5SLC9A2MTNR1BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120088809-A1 | 1-(2-ALKYL-2,3-DIHYDRO-BENZOFURAN-4-YL)-PYRROLIDIN-3-YLAMINE ACYL COMPOUNDS | FERRER INTERNACIONAL, S.A. (ES) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088809-A1 | 1-(2-ALKYL-2,3-DIHYDRO-BENZOFURAN-4-YL)-PYRROLIDIN-3-YLAMINE ACYL COMPOUNDS | MTNR1A, MTNR1B, TPH2 | SLC9A1 3825/4885SLC9A5 3498/4885SLC9A2 3591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.