SCHEMBL6951089

SCHEMBL6951089

O=C1CCC(=O)N1c1nc(N2C(=O)CCC2=O)nc(N2C(=O)CCC2=O)n1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.40
HPGD P15428 2/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.34
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA9 Q16790 2/20 0.33
POLB P06746 1/20 0.33
DPP4 P27487 1/20 0.32
CA2 P00918 1/20 0.32
TP53 P04637 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
KMT2A Q03164 3/20 0.31
NPC1 O15118 1/20 0.31
PKM P14618 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
RAF1 P04049 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8162676 0.88 KMT2A (0.41) RECQLHPGDKDM4EALDH1A1POLB
SCHEMBL6946151 0.87 RECQL (0.34) RECQLHPGDKDM4EALDH1A1TSHR
SCHEMBL8162746 0.87 RECQL (0.34) RECQLHPGDKDM4EALDH1A1TSHR
SCHEMBL1033693 0.82 RECQL (0.34) RECQLHPGDKDM4EALDH1A1TSHR
SCHEMBL8157034 0.78 KMT2A (0.35) ALDH1A1POLBDPP4KMT2ALMNA
SCHEMBL15952641 0.73 LMNA (0.44) RECQLHPGDKDM4EALDH1A1POLB
SCHEMBL15952680 0.73 ALDH1A1 (0.42) RECQLHPGDKDM4EALDH1A1POLB
SCHEMBL6947659 0.71 RECQL (0.34) RECQLHPGDKDM4EALDH1A1TSHR
SCHEMBL8157954 0.69 RECQL (0.33) RECQLHPGDKDM4EALDH1A1TSHR
SCHEMBL15953384 0.68 KMT2A (0.39) RECQLCA12CA1CA9POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6013797-A CURING AGENT WHICH CROSSLINKS RESINS BY DECYCLIZATION WITHOUT RELEASING VOLATILE ORGANIC COMPOUNDS; FORMALDEHYDE-FREE CYTEC TECHNOLOGY CORP. (US) 2000-01-11 US claimed
EP-0885214-A1 CYCLIC IMIDO-1,3,5-TRIAZINE CROSSLINKING AGENTS Cytec Technology Corp. (US) 1998-12-23 EP claimed
WO-1997031914-A1 CYCLIC IMIDO-1,3,5-TRIAZINE CROSSLINKING AGENTS CYTEC TECHNOLOGY CORP. (US) 1997-09-04 WO claimed
EP-1279673-A1 Imidotriazine derivatives Agrolinz Melamin GmbH (AT) 2003-01-29 EP disclosed
US-6013797-A CURING AGENT WHICH CROSSLINKS RESINS BY DECYCLIZATION WITHOUT RELEASING VOLATILE ORGANIC COMPOUNDS; FORMALDEHYDE-FREE CYTEC TECHNOLOGY CORP. (US) 2000-01-11 US disclosed
EP-0885214-A1 CYCLIC IMIDO-1,3,5-TRIAZINE CROSSLINKING AGENTS Cytec Technology Corp. (US) 1998-12-23 EP disclosed
US-5807929-A Cyclic imido-1,3,5-triazine crosslinking agents CYTEC TECHNOLOGY CORP. (US) 1998-09-15 US disclosed
WO-1997031914-A1 CYCLIC IMIDO-1,3,5-TRIAZINE CROSSLINKING AGENTS CYTEC TECHNOLOGY CORP. (US) 1997-09-04 WO disclosed