SCHEMBL1033693

SCHEMBL1033693

Nc1nc(N)nc(N2C(=O)CCC2=O)n1

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.34
KMT2A Q03164 1/20 0.33
DPP4 P27487 1/20 0.32
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
HRH4 Q9H3N8 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6946151 0.95 RECQL (0.34) RECQLKMT2ADPP4CA12CA1
SCHEMBL8157034 0.86 KMT2A (0.35) KMT2ADPP4ALDH1A1
SCHEMBL6951089 0.82 RECQL (0.40) RECQLKMT2ADPP4CA12CA1
SCHEMBL8157954 0.77 RECQL (0.33) RECQLKMT2ACA12CA1CA2
SCHEMBL8162676 0.72 KMT2A (0.41) RECQLKMT2ADPP4KDM4EALDH1A1
SCHEMBL8162746 0.71 RECQL (0.34) RECQLKMT2AKDM4EALDH1A1HPGD
SCHEMBL11573348 0.68 CYP1A2 (0.30)
SCHEMBL2475981 0.67 GAA (0.32) CA12CA1CA2CA9
Hydrazine SCHEMBL28292815 0.66 CASP1 (0.47) KDM4EALDH1A1
SCHEMBL5322518 0.66 ALPL (0.44) KMT2ACA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3544963-B1 METHOD FOR ALKYLATING AN AMINO COMPOUND BOREALIS AGROLINZ MELAMINE (AT) 2020-11-04 EP disclosed
EP-3544963-A1 METHOD FOR ALKYLATING AN AMINO COMPOUND Borealis Agrolinz Melamine GmbH (AT) 2019-10-02 EP disclosed
WO-2018096011-A1 METHOD FOR ALKYLATING AN AMINO COMPOUND BOREALIS AGROLINZ MELAMINE GMBH (AT) 2018-05-31 WO disclosed
EP-3327009-A1 METHOD FOR ALKYLATING AN AMINO COMPOUND Borealis Agrolinz Melamine GmbH (AT) 2018-05-30 EP disclosed
EP-2268610-B1 METHOD FOR PRODUCING A COMPOUND WITH AT LEAST ONE AT LEAST MONOSUBSTITUTED AMINO GROUP BOREALIS AGROLINZ MELAMINE (AT) 2016-08-03 EP disclosed
US-8871842-B2 Method for producing a compound with at least one at least monosubstituted amino group BOREALIS AGROLINZ MELAMINE GMBH (AT) 2014-10-28 US disclosed
EP-1521805-B1 AMINOPLAST MOLDING COMPOUNDS FOR PRODUCTS EXHIBITING AN IMPROVED FLEXIBILITY AND AMINOPLAST PRODUCTS EXHIBITING AN IMPROVED FLEXIBILITY BOREALIS AGROLINZ MELAMINE (AT) 2014-05-21 EP disclosed
US-20110178212-A1 Method for Producing a Compound with at Least One at Least Monosubstituted Amino Group BOREALIS AGROLINZ MELAMINE GMBH (AT) 2011-07-21 US disclosed
US-20110105654-A1 Method for Producing a Compound with at Least One at Least Monosubstituted Amino Group BOREALIS AGROLINZ MELAMINE GMBH (AT) 2011-05-05 US disclosed
EP-2276749-A1 METHOD FOR PRODUCING A COMPOUND WITH AT LEAST ONE AT LEAST MONOSUBSTITUTED AMINO GROUP Borealis Agrolinz Melamine GmbH (AT) 2011-01-26 EP disclosed
CN-100345887-C Pre-impregnating agents for high-resistant and elastic composite fibres AMI AGROLINZ MELAMINE INT GMBH (AT) 2007-10-31 CN disclosed
EP-1603969-B1 PRE-IMPREGNATING AGENTS FOR HIGH-RESISTANT AND ELASTIC COMPOSITE FIBRES AMI AGROLINZ MELAMINE INT GMBH (AT) 2007-10-03 EP disclosed
US-20070048522-A1 Prepregs for fiber composites having high strength and resilience AMI - AGROLINZ MELAMINE INTERNATIONAL GMBH (AT) 2007-03-01 US disclosed
US-20060100317-A1 Aminoplast molding compounds for products exhibiting an improved flexibility and aminoplast products exhibiting and improved flexibility AMI - AGROLINZ MELAMINE INTERNATIONAL GMBH (AT) 2006-05-11 US disclosed
CN-1761705-A Pre-impregnating agents for high-resistant and elastic composite fibres AMI AGROLINZ MELAMINE INT GMBH (AT) 2006-04-19 CN disclosed
EP-1603969-A1 PRE-IMPREGNATING AGENTS FOR HIGH-RESISTANT AND ELASTIC COMPOSITE FIBRES AMI Agrolinz Melamine International GmbH (AT) 2005-12-14 EP disclosed
EP-1521805-A1 AMINOPLAST MOLDING COMPOUNDS FOR PRODUCTS EXHIBITING AN IMPROVED FLEXIBILITY AND AMINOPLAST PRODUCTS EXHIBITING AN IMPROVED FLEXIBILITY AMI - Agrolinz Melamine International GmbH (AT) 2005-04-13 EP disclosed
WO-2004083275-A1 THERMOSETTING MOULDABLE MATERIAL PROVIDED WITH IMPROVED PROCESSABILITY AMI AGROLINZ MELAMINE INTERNATIONAL GMBH (AT) 2004-09-30 WO disclosed
WO-2004083288-A1 PRE-IMPREGNATING AGENTS FOR HIGH-RESISTANT AND ELASTIC COMPOSITE FIBRES AMI AGROLINZ MELAMINE INTERNATIONAL GMBH (AT) 2004-09-30 WO disclosed
WO-2003106558-A1 AMINOPLAST MOLDING COMPOUNDS FOR PRODUCTS EXHIBITING AN IMPROVED FLEXIBILITY AND AMINOPLAST PRODUCTS EXHIBITING AN IMPROVED FLEXIBILITY AGROLINZ MELAMIN GMBH (AT) 2003-12-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110178212-A1 Method for Producing a Compound with at Least One at Least Monosubstituted Amino Group INMT, AADAT, AANAT RECQL 4848/4885KMT2A 1316/4885DPP4 2145/4885
US-20110105654-A1 Method for Producing a Compound with at Least One at Least Monosubstituted Amino Group GNMT, PAM, SMOX RECQL 4666/4885KMT2A 278/4885DPP4 1477/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.