SCHEMBL6947659

SCHEMBL6947659

O=C1CCC(=O)N1c1ncncn1

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.34
LMNA P02545 1/20 0.33
CA12 O43570 2/20 0.32
CA1 P00915 2/20 0.32
CA9 Q16790 2/20 0.32
POLB P06746 1/20 0.32
HPGD P15428 2/20 0.31
CA2 P00918 1/20 0.31
TP53 P04637 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HSP90AA1 P07900 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15952680 0.78 ALDH1A1 (0.42) RECQLLMNAPOLBHPGDL3MBTL1
SCHEMBL1706734 0.73 BCHE (0.43) HSP90AA1
SCHEMBL15953384 0.73 KMT2A (0.39) RECQLLMNACA12CA1CA9
SCHEMBL8157954 0.73 RECQL (0.33) RECQLCA12CA1CA9HPGD
SCHEMBL6951089 0.71 RECQL (0.40) RECQLLMNACA12CA1CA9
SCHEMBL9007009 0.70 L3MBTL1 (0.41) LMNAHPGDL3MBTL1ALDH1A1TSHR
SCHEMBL15953109 0.70 KMT2A (0.41) RECQLLMNAPOLBKDM4EALDH1A1
SCHEMBL8162536 0.69 ALPL (0.44) HPGDALDH1A1
SCHEMBL9959877 0.68 HPGD (0.57) HPGD
SCHEMBL9822038 0.67 SIGMAR1 (0.37) HPGDL3MBTL1KDM4EALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1279673-A1 Imidotriazine derivatives Agrolinz Melamin GmbH (AT) 2003-01-29 EP disclosed
US-6013797-A CURING AGENT WHICH CROSSLINKS RESINS BY DECYCLIZATION WITHOUT RELEASING VOLATILE ORGANIC COMPOUNDS; FORMALDEHYDE-FREE CYTEC TECHNOLOGY CORP. (US) 2000-01-11 US disclosed
EP-0885214-A1 CYCLIC IMIDO-1,3,5-TRIAZINE CROSSLINKING AGENTS Cytec Technology Corp. (US) 1998-12-23 EP disclosed
US-5807929-A Cyclic imido-1,3,5-triazine crosslinking agents CYTEC TECHNOLOGY CORP. (US) 1998-09-15 US disclosed
WO-1997031914-A1 CYCLIC IMIDO-1,3,5-TRIAZINE CROSSLINKING AGENTS CYTEC TECHNOLOGY CORP. (US) 1997-09-04 WO disclosed