Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 4/20 | 0.44 |
| ▸ | ICAM1 | P05362 | 4/20 | 0.44 |
| ▸ | ITGAL | P20701 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29522638 | 1.00 | ITGB2 (0.44) | ITGB2ICAM1ITGALSMN1; SMN2LMNA | |
| SCHEMBL692549 | 0.81 | CTSS (0.47) | ITGB2ICAM1ITGALLMNA | |
| SCHEMBL692547 | 0.81 | CTSS (0.47) | ITGB2ICAM1ITGALLMNA | |
| SCHEMBL38327 | 0.81 | L3MBTL1 (0.49) | ITGB2ICAM1ITGALLMNAITGA4 | |
| SCHEMBL10065865 | 0.78 | CTSS (0.41) | SMN1; SMN2 | |
| SCHEMBL7136191 | 0.77 | APAF1 (0.41) | SMN1; SMN2LMNAPOLBL3MBTL1 | |
| SCHEMBL1529787 | 0.76 | PTPN1 (0.55) | ITGB1 | |
| SCHEMBL4584520 | 0.76 | PTPN1 (0.55) | ITGB1 | |
| SCHEMBL8986521 | 0.76 | SLC1A1 (0.56) | — | |
| SCHEMBL31754259 | 0.76 | SLC1A1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421893-A2 | SHORT-CHAIN PEPTIDES AS PARATHYROID HORMONE (PTH) RECEPTOR AGONIST | Cadila Healthcare Limited (IN) | 2012-02-29 | — | — | EP | claimed |
| WO-2010128521-A2 | SHORT-CHAIN PEPTIDES AS PARATHYROID HORMONE (PTH) RECEPTOR AGONIST | CADILA HEALTHCARE LIMITED (IN) | 2010-11-11 | — | — | WO | claimed |
| CN-114585637-A | MASP inhibiting compounds and uses thereof | 拜耳公司 | 2022-06-03 | — | — | CN | disclosed |
| WO-2012120532-A2 | CYCLIC SHORT CHAIN PEPTIDES | CADILA HEALTHCARE LIMITED (IN) | 2012-09-13 | — | — | WO | disclosed |
| EP-2421893-A2 | SHORT-CHAIN PEPTIDES AS PARATHYROID HORMONE (PTH) RECEPTOR AGONIST | Cadila Healthcare Limited (IN) | 2012-02-29 | — | — | EP | disclosed |
| WO-2010128521-A2 | SHORT-CHAIN PEPTIDES AS PARATHYROID HORMONE (PTH) RECEPTOR AGONIST | CADILA HEALTHCARE LIMITED (IN) | 2010-11-11 | — | — | WO | disclosed |