Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.43 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8180461 | 0.83 | ALDH1A1 (0.41) | ALDH1A1TSHRADRB2ADRB1ADRB3 | |
| SCHEMBL128588 | 0.81 | CA12 (0.50) | TSHRRAB9ANPC1HTTSMN1; SMN2 | |
| SCHEMBL6568994 | 0.81 | ALDH1A1 (0.38) | ALDH1A1TSHRPLA2G1BATG4BRAB9A | |
| SCHEMBL6953148 | 0.80 | ALDH1A1 (0.55) | ALDH1A1TSHRPLA2G1BATG4BADRB2 | |
| Benzoic Acid 2-Methylpropyl Ester SCHEMBL20530394 | 0.79 | TSHR (0.69) | ALDH1A1TSHRPLA2G1BATG4BADRB2 | |
| Benzoic Acid 2-Methylpropyl Ester SCHEMBL298176 | 0.79 | TSHR (0.69) | ALDH1A1TSHRPLA2G1BATG4BADRB2 | |
| SCHEMBL127761 | 0.79 | LMNA (0.64) | ALDH1A1TSHRJMJD6RAB9AMAPT | |
| SCHEMBL6345356 | 0.78 | ALDH1A1 (0.39) | ALDH1A1TSHRNPC1HTTMAPT | |
| SCHEMBL5846076 | 0.78 | TDP1 (0.39) | ALDH1A1TSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL128815 | 0.78 | CA12 (0.50) | ALDH1A1TSHRJMJD6RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936218-B1 | BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARM CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6387938-B1 | Benzimidazole derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-0936218-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |