Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | CA7 | P43166 | 4/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL127761 | 0.86 | LMNA (0.64) | ESR1LMNACYP1A2CYP3A4TSHR | |
| SCHEMBL9070423 | 0.85 | SMN1; SMN2 (0.51) | ESR1LMNATSHRSMN1; SMN2CYP4F2 | |
| SCHEMBL8180461 | 0.84 | ALDH1A1 (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8180463 | 0.84 | SMN1; SMN2 (0.50) | ESR1LMNACYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL125941 | 0.83 | L3MBTL1 (0.56) | ESR1LMNACYP1A2CYP3A4TSHR | |
| SCHEMBL1510145 | 0.83 | TP53 (0.51) | SMN1; SMN2NPC1RAB9ACYP4F2CYP4A11 | |
| SCHEMBL5541610 | 0.82 | LMNA (0.56) | ESR1LMNACYP1A2CYP3A4TSHR | |
| SCHEMBL5846076 | 0.82 | TDP1 (0.39) | LMNACYP1A2CYP3A4MAOATSHR | |
| SCHEMBL6952025 | 0.81 | ALDH1A1 (0.53) | LMNATSHRSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8171785 | 0.81 | TSHR (0.53) | CA1CA2ESR1ESR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 911 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230131260-A1 | SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS | SYNGENTA CROP PROTECTION AG (CH) | 2023-04-27 | — | — | US | claimed |
| US-20220389009-A1 | SUBSTITUTED 1,6-NAPHTHYRIDINE INHIBITORS OF CDK5 | GFB (ABC), LLC | 2022-12-08 | — | — | US | claimed |
| CN-114761000-A | Substituted 1, 6-naphthyridine inhibitors of CDK5 | 金翅雀生物公司 | 2022-07-15 | — | — | CN | claimed |
| US-20220151991-A1 | SMALL MOLECULE GRB2 STABILIZERS FOR RAS MAP KINASE INHIBITION | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2022-05-19 | — | — | US | claimed |
| US-11274083-B2 | Substituted thiophenyl uracils, salts thereof and the use thereof as herbicidal agents | SYNGENTA CROP PROTECTION AG (CH) | 2022-03-15 | — | — | US | claimed |
| EP-3728235-B1 | SUBSTITUTED THIOPHENYLURACILS , THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS | SYNGENTA CROP PROTECTION AG (CH) | 2022-02-09 | — | — | EP | claimed |
| EP-3728237-B1 | SUBSTITUTED THIOPHENYLURACILS , THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS | SYNGENTA CROP PROTECTION AG (CH) | 2022-02-09 | — | — | EP | claimed |
| EP-3937919-A1 | SMALL MOLECULE GRB2 STABILIZERS FOR RAS MAP KINASE INHIBITION | Board of Regents, The University of Texas System (US) | 2022-01-19 | — | — | EP | claimed |
| WO-2022011274-A1 | SUBSTITUTED 1,6-NAPHTHYRIDINE INHIBITORS OF CDK5 | GOLDFINCH BIO, INC. (US) | 2022-01-13 | — | — | WO | claimed |
| CN-111087305-B | Beta-fluoroalkyl cinnamate compound and preparation method thereof | 南京工业大学 | 2021-08-27 | — | — | CN | claimed |
| EP-0363223-A2 | 3-Aryloxymethyl-cephalosporin derivatives, their preparation and their medical use | Sankyo Company Limited (JP) | 1990-04-11 | — | — | EP | claimed |
| EP-0221211-B1 | USE OF SECONDARY AMIDE COMPOUNDS FOR THE MANUFACTURE OF MEDICAMENTS FOR THE TREATMENT OF DERMATOLOGICAL INFLAMMATION | UNILEVER PLC (GB) | 1989-01-11 | — | — | EP | claimed |
| US-4769325-A | 2-(Allenyl)penicillins | BALDWIN JACK E (GB) | 1988-09-06 | — | — | US | claimed |
| US-4742083-A | Method of relieving pain and inflammatory conditions employing substituted salicylamides | LEVER BROTHERS COMPANY (US) | 1988-05-03 | — | — | US | claimed |
| US-4725590-A | SKIN DISORDERS; ANTIACNE SHAMPOO AND SOAP | LEVER BROTHERS COMPANY (US) | 1988-02-16 | — | — | US | claimed |
| EP-0223515-A2 | Oral compositions comprising salicylamides and zinc salts for the synergistic inhibition of dental plaque | UNILEVER PLC (GB) | 1987-05-27 | — | — | EP | claimed |
| EP-0221211-A1 | Use of secondary amide compounds for the manufacture of medicaments for the treatment of dermatological inflammation | UNILEVER PLC (GB) | 1987-05-13 | — | — | EP | claimed |
| EP-0218323-A1 | 2-Propadienyl penicillin derivatives and intermediates | Baldwin, Jack Edward (GB) | 1987-04-15 | — | — | EP | claimed |
| US-4647452-A | Oral compositions of salicylamides and zinc salts for the synergistic inhibition of dental plaque | LEVER BROTHERS COMPANY (US) | 1987-03-03 | — | — | US | claimed |
| US-4560549-A | TOPICAL AND SYSTEMICAL; HUMANS ANIMALS; MICROBIOCIDES | LEVER BROTHERS COMPANY (US) | 1985-12-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220151991-A1 | SMALL MOLECULE GRB2 STABILIZERS FOR RAS MAP KINASE INHIBITION | GRB2, KRAS, HRAS | CA12 4588/4885CA1 4699/4885CA2 3805/4885 |
| US-11274083-B2 | Substituted thiophenyl uracils, salts thereof and the use thereof as herbicidal agents | UNG, TYMP, TYMS | CA12 4133/4885CA1 3063/4885CA2 2447/4885 |
| US-20220389009-A1 | SUBSTITUTED 1,6-NAPHTHYRIDINE INHIBITORS OF CDK5 | CDK5, CDK5R1, PKD1 | CA12 4550/4885CA1 2682/4885CA2 2907/4885 |
| US-20230131260-A1 | SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS | UNG, TYMP, TYMS | CA12 4178/4885CA1 3077/4885CA2 2425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.