Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29286236 | 0.81 | SMN1; SMN2 (0.44) | MAPK1SMN1; SMN2TSHRNAPRTHSD17B10 | |
| SCHEMBL11465233 | 0.76 | LMNA (0.41) | LMNASMN1; SMN2ALDH1A1POLBKDM4E | |
| SCHEMBL6947890 | 0.73 | NOS3 (0.47) | PTGS1PTGS2KDM4CALDH1A1NAPRT | |
| SCHEMBL22977449 | 0.73 | MAPT (0.44) | LMNAALDH1A1POLBMAPTKDM4E | |
| SCHEMBL17610582 | 0.73 | LMNA (0.40) | LMNAALDH1A1POLBMAPTKDM4E | |
| SCHEMBL25193541 | 0.73 | LMNA (0.43) | LMNASMN1; SMN2ALDH1A1TSHRNAPRT | |
| SCHEMBL30449348 | 0.73 | MAPT (0.44) | LMNAALDH1A1POLBMAPTKDM4E | |
| SCHEMBL25191601 | 0.71 | LMNA (0.38) | LMNAALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL25194989 | 0.71 | MAPK8 (0.36) | LMNASMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL27656965 | 0.70 | ACHE (0.41) | LMNAMAPK1SMN1; SMN2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674623-B1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2003-04-09 | — | — | EP | disclosed |
| US-6403578-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | SMITHKLINE BEECHAM CORPORATION | 2002-06-11 | — | — | US | disclosed |