SCHEMBL69535

SCHEMBL69535

Cc1cc(C)c(C(=O)P(C)(=O)c2ccccc2)c(C)c1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.39
LMNA P02545 2/20 0.39
NPC1 O15118 4/20 0.39
RAB9A P51151 4/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
MAPT P10636 2/20 0.39
KMT2A Q03164 6/20 0.37
MEN1 O00255 4/20 0.37
HPGD P15428 2/20 0.37
CFTR P13569 1/20 0.37
CA2 P00918 1/20 0.36
CA4 P22748 1/20 0.36
CA5A P35218 1/20 0.36
HTT P42858 1/20 0.36
FKBP5 Q13451 1/20 0.36
USP2 O75604 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Potassium SCHEMBL29365565 0.86 LMNA (0.42) ESR1LMNANPC1RAB9ASMN1; SMN2
SCHEMBL7175016 0.86 ESR1 (0.41) ESR1NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL7183332 0.85 KCNK9 (0.40) ESR1LMNASMN1; SMN2MAPTKMT2A
SCHEMBL27651 0.84 LMNA (0.43) ESR1LMNANPC1RAB9ASMN1; SMN2
SCHEMBL27967065 0.84 LMNA (0.43) ESR1LMNANPC1RAB9ASMN1; SMN2
SCHEMBL15158 0.84 LMNA (0.40) ESR1LMNANPC1RAB9ASMN1; SMN2
SCHEMBL7177683 0.83 KMT2A (0.38) ESR1NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL25408502 0.83 LMNA (0.42) ESR1LMNANPC1RAB9ASMN1; SMN2
SCHEMBL17376918 0.83 LMNA (0.42) ESR1LMNANPC1RAB9ASMN1; SMN2
SCHEMBL18334662 0.83 LMNA (0.42) ESR1LMNANPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025124047-A1 PHOTOSENSITIVE THERMOSETTING RESIN COMPOSITION, DRY FILM, CURED PRODUCT, AND ELECTRONIC COMPONENT COMPRISING CURED PRODUCT 太阳油墨(苏州)有限公司 2025-06-19 WO disclosed
WO-2025066478-A1 MELAMINE-FREE ALKALINE DEVELOPABLE RESIN COMPOSITION, DRY FILM, CURED PRODUCT AND ELECTRONIC COMPONENT HAVING SAID CURED PRODUCT 太阳油墨(苏州)有限公司 2025-04-03 WO disclosed
CN-118043739-A Photosensitive resin composition, cured product, printed wiring board, and method for producing printed wiring board 太阳控股株式会社 2024-05-14 CN disclosed
US-11912800-B2 Amide-functionalized polymerization initiators and their use in the manufacture of ophthalmic lenses JOHNSON & JOHNSON VISION CARE, INC. (US) 2024-02-27 US disclosed
EP-3861002-B1 ORGANOSILICON COMPOUND, METHOD FOR PRODUCING THEREOF, AND USE THEREOF DOW TORAY CO LTD (JP) 2023-11-29 EP disclosed
US-11385541-B2 Radiation-curable resin composition and production method thereof CENTRO TECNOLOGICO DE NANOMATERIALES AVANZADOS, S.L. (ES) 2022-07-12 US disclosed
WO-2020072269-A1 ORGANOSILICON COMPOUND, METHOD FOR PRODUCING THEREOF, AND USE THEREOF DOW TORAY CO., LTD. (JP) 2020-04-09 WO disclosed
US-10040916-B2 Functional polymer membrane and method for producing same FUJIFILM CORPORATION (JP) 2018-08-07 US disclosed
US-20180044545-A1 PHOTOCURABLE INKS FOR INDIRECT PRINTING METHOD XEROX CORPORATION 2018-02-15 US disclosed
US-9795955-B2 Curable composition and cured polymer product FUJIFILM CORPORATION (JP) 2017-10-24 US disclosed
US-20070021522-A1 for protecting xerographic images on substrates subjected to abrasives, heat, and/or sunlight since the compositions protect such images from cracking, fading, and smearing; silicone oil as release agent XEROX CORPORATION (US) 2007-01-25 US disclosed
US-7166406-B2 Prevention or reduction of thermal cracking on toner-based prints XEROX CORPORATION (US) 2007-01-23 US disclosed
US-20070007698-A1 Method of producting three-dimensional model FUJIFILM CORPORATION (JP) 2007-01-11 US disclosed
US-20070007698-A1 Method of producting three-dimensional model FUJIFILM CORPORATION (JP) 2007-01-11 US disclosed
CN-1200943-C Organometallic acyl-aryl phosphine CIBA SC HOLDING AG (CH) 2005-05-11 CN disclosed
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 US disclosed
CN-1308081-A Organometallic acyl-aryl phosphine CIBA SC HOLDING AG (CH) 2001-08-15 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 ESR1 3736/4885LMNA 3241/4885NPC1 772/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 ESR1 3621/4885LMNA 3247/4885NPC1 872/4885
US-11912800-B2 Amide-functionalized polymerization initiators and their use in the manufacture of ophthalmic lenses CRYAA, UACA, CRYAB ESR1 3064/4885LMNA 1459/4885NPC1 4695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.