Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6657804 | 0.90 | SMN1; SMN2 (0.46) | MAPTALDH1A1HPGDATMMEN1 | |
| SCHEMBL6965274 | 0.89 | PI4KB (0.41) | RBP4THRBKDM4EMAPTHSD17B10 | |
| SCHEMBL8705064 | 0.84 | HTR1A (0.52) | RBP4THRBKDM4EMAPTHSD17B10 | |
| SCHEMBL8699470 | 0.83 | KMT2A (0.51) | RBP4KDM4EMAPTHSD17B10ALDH1A1 | |
| SCHEMBL8705983 | 0.83 | MAPT (0.57) | RBP4KDM4EMAPTHSD17B10ALDH1A1 | |
| SCHEMBL8700940 | 0.83 | RBP4 (0.61) | RBP4KDM4EMAPTALDH1A1GAA | |
| SCHEMBL8705260 | 0.83 | RBP4 (0.55) | RBP4KDM4EMAPTGAAP2RY12 | |
| SCHEMBL8704636 | 0.83 | KMT2A (0.57) | RBP4KDM4EMAPTHSD17B10ALDH1A1 | |
| SCHEMBL8700061 | 0.83 | MAPT (0.57) | RBP4KDM4EMAPTALDH1A1GAA | |
| SCHEMBL7139732 | 0.83 | RBP4 (0.43) | RBP4KDM4EMAPTHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850222-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6028195-A | AN ANTITUMOR AGENT WITH VERY LOW TOXICITIES | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-02-22 | — | — | US | disclosed |