Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | HTR1D | P28221 | 3/20 | 0.41 |
| ▸ | HTR1B | P28222 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | RBP4 | P02753 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6954299 | 0.89 | RBP4 (0.41) | PI4KBTHRBHTR1AHTR1DHTR1B | |
| SCHEMBL7139732 | 0.85 | RBP4 (0.43) | HTR1AHTR1DHTR1BMAPTALDH1A1 | |
| SCHEMBL6559720 | 0.84 | MAPT (0.39) | PI4KBHTR1AHTR1DHTR1BMAPT | |
| SCHEMBL8701091 | 0.83 | THRB (0.55) | THRBHTR1AHTR1DHTR1BMAPT | |
| SCHEMBL6966645 | 0.82 | MAPT (0.60) | HTR1AHTR1DHTR1BMAPTLMNA | |
| SCHEMBL6961499 | 0.82 | MAPT (0.48) | PI4KBTHRBHTR1AHTR1DHTR1B | |
| SCHEMBL8705827 | 0.82 | LMNA (0.61) | HTR1AHTR1DHTR1BMAPTLMNA | |
| SCHEMBL9058218 | 0.82 | PANK3 (0.62) | HTR1AHTR1DHTR1BMAPTLMNA | |
| SCHEMBL8703774 | 0.82 | THRB (0.47) | THRBHTR1AHTR1DHTR1BMAPT | |
| SCHEMBL6954279 | 0.81 | KMT2A (0.49) | PI4KBMAPTLMNAALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850222-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6028195-A | AN ANTITUMOR AGENT WITH VERY LOW TOXICITIES | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-02-22 | — | — | US | disclosed |