Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | PRMT5 | O14744 | 7/20 | 0.48 |
| ▸ | WDR77 | Q9BQA1 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15012018 | 0.89 | ALDH1A1 (0.50) | ALDH1A1KDM4EKDM1AMAOB | |
| SCHEMBL9637698 | 0.84 | ALDH1A1 (0.56) | ALDH1A1PRMT5WDR77CNR1CNR2 | |
| Ammonia Solution, Strong SCHEMBL9637696 | 0.84 | ALDH1A1 (0.59) | ALDH1A1PRMT5WDR77KDM4ECYP1A2 | |
| SCHEMBL2807484 | 0.83 | KMT2A (0.47) | ALDH1A1KDM4ETSHRKDM1AMAOB | |
| SCHEMBL663312 | 0.83 | ALDH1A1 (0.54) | ALDH1A1TSHRCARM1PRMT6POLB | |
| SCHEMBL1040185 | 0.82 | ALDH1A1 (0.88) | ALDH1A1TSHRKDM1AMAOAMAOB | |
| SCHEMBL89233 | 0.82 | ALDH1A1 (0.66) | ALDH1A1KDM4ETSHRCNR1CNR2 | |
| SCHEMBL4782932 | 0.81 | ALDH1A1 (0.52) | ALDH1A1PRMT5WDR77KDM4ECARM1 | |
| SCHEMBL89319 | 0.81 | ALDH1A1 (0.49) | ALDH1A1KDM4ECYP1A2CYP2D6CYP2C19 | |
| SCHEMBL15012151 | 0.80 | MEN1 (0.42) | ALDH1A1PRMT5WDR77KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012085935-A2 | COMPOUNDS AS INHIBITORS OF RENIN | CADILA HEALTHCARE LIMITED (IN) | 2012-06-28 | — | — | WO | disclosed |
| US-20120115907-A1 | NOVEL COMPOUNDS AS INHIBITORS OF RENIN | CADILA HEALTHCARE LIMITED (IN) | 2012-05-10 | — | — | US | disclosed |
| EP-2421828-A2 | PIPERIDINE DERIVATIVES AS INHIBITORS OF RENIN | Cadila Healthcare Limited (IN) | 2012-02-29 | — | — | EP | disclosed |
| WO-2010122580-A2 | NOVEL COMPOUNDS AS INHIBITORS OF RENIN | CADILA HEALTHCARE LIMITED (IN) | 2010-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115907-A1 | NOVEL COMPOUNDS AS INHIBITORS OF RENIN | REN, ACE, AGTR1 | ALDH1A1 1307/4885PRMT5 2530/4885WDR77 2948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.