Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MGLL | Q99685 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967673 | 0.77 | HSP90AA1 (0.35) | HPGDALDH1A1KMT2APKMHSP90AA1 | |
| SCHEMBL6966738 | 0.76 | HPGD (0.34) | HPGDALDH1A1KMT2APKMFFAR1 | |
| SCHEMBL6966721 | 0.75 | HPGD (0.33) | HPGDALDH1A1KMT2APKMFFAR1 | |
| SCHEMBL6963138 | 0.70 | — | — | |
| SCHEMBL10144329 | 0.70 | TSHR (0.46) | HPGDALDH1A1KMT2AFFAR1MAPT | |
| SCHEMBL6683261 | 0.69 | HPGD (0.46) | HPGDALDH1A1KMT2ANPSR1FFAR1 | |
| Fluoride SCHEMBL27784131 | 0.69 | TSHR (0.45) | HPGDALDH1A1KMT2AFFAR1MAPT | |
| SCHEMBL12319725 | 0.66 | HPGD (0.42) | HPGDALDH1A1KMT2ANPSR1FFAR1 | |
| SCHEMBL6832557 | 0.66 | HPGD (0.42) | HPGDALDH1A1KMT2ANPSR1FFAR1 | |
| SCHEMBL7776861 | 0.66 | ALDH1A1 (0.45) | HPGDALDH1A1KMT2APKMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |