Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967673 | 0.86 | HSP90AA1 (0.35) | HPGDALDH1A1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL6966721 | 0.84 | HPGD (0.33) | HPGDALDH1A1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL6955110 | 0.76 | HPGD (0.33) | HPGDALDH1A1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL10144329 | 0.72 | TSHR (0.46) | HPGDALDH1A1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL6683261 | 0.72 | HPGD (0.46) | HPGDALDH1A1SMN1; SMN2HSD17B10MAPT | |
| Fluoride SCHEMBL27784131 | 0.71 | TSHR (0.45) | HPGDALDH1A1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL7776861 | 0.69 | ALDH1A1 (0.45) | HPGDALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL6832557 | 0.69 | HPGD (0.42) | HPGDALDH1A1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL12319725 | 0.69 | HPGD (0.42) | HPGDALDH1A1SMN1; SMN2HSD17B10MAPT | |
| SCHEMBL6968617 | 0.69 | HPGD (0.42) | HPGDALDH1A1SMN1; SMN2HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |