Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 3/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | PHGDH | O43175 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966738 | 0.86 | HPGD (0.34) | MGLLALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL6966721 | 0.81 | HPGD (0.33) | MGLLALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL6955110 | 0.77 | HPGD (0.33) | HSP90AA1HSP90AB1MGLLFAAHPHGDH | |
| SCHEMBL13213809 | 0.72 | ALDH1A1 (0.44) | HSP90AA1HSP90AB1MGLLFAAHPHGDH | |
| SCHEMBL10144329 | 0.70 | TSHR (0.46) | MGLLALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL6971307 | 0.70 | — | — | |
| SCHEMBL12657170 | 0.70 | ELANE (0.39) | HSP90AA1HSP90AB1MGLLFAAHPHGDH | |
| SCHEMBL6683261 | 0.69 | HPGD (0.46) | MGLLALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL6827887 | 0.69 | HPGD (0.37) | MGLLALDH1A1HPGDMAPTKMT2A | |
| Fluoride SCHEMBL27784131 | 0.69 | TSHR (0.45) | MGLLALDH1A1HPGDMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |