Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 5/20 | 0.38 |
| ▸ | F3 | P13726 | 5/20 | 0.38 |
| ▸ | PPARG | P37231 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | PPARD | Q03181 | 4/20 | 0.36 |
| ▸ | PPARA | Q07869 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | FABP4 | P15090 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955242 | 1.00 | F7 (0.38) | F7F3PPARGALDH1A1PPARD | |
| SCHEMBL6973668 | 0.89 | TAS1R3 (0.30) | — | |
| SCHEMBL6973671 | 0.89 | TAS1R3 (0.30) | — | |
| SCHEMBL2936006 | 0.85 | F7 (0.45) | F7F3PPARGALDH1A1PPARD | |
| SCHEMBL6958514 | 0.81 | FFAR1 (0.31) | PPARGALDH1A1FFAR1CYP19A1PTGS1 | |
| SCHEMBL6958509 | 0.81 | FFAR1 (0.31) | PPARGALDH1A1FFAR1CYP19A1PTGS1 | |
| SCHEMBL11122755 | 0.79 | F7 (0.41) | F7F3PPARGALDH1A1PPARD | |
| SCHEMBL17628514 | 0.79 | F7 (0.41) | F7F3PPARGALDH1A1PPARD | |
| SCHEMBL6955244 | 0.78 | F7 (0.40) | F7F3PPARGALDH1A1PPARD | |
| SCHEMBL11121781 | 0.78 | FAAH (0.45) | F7F3PPARGALDH1A1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |