Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | UTRN | P46939 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1001327 | 0.71 | FAAH (0.44) | TP53MAPTNPC1RAB9A | |
| SCHEMBL1002617 | 0.69 | USP1 (0.42) | TP53MAPTNPC1RAB9A | |
| SCHEMBL1002859 | 0.63 | FFAR4 (0.33) | NPC1RAB9A | |
| SCHEMBL14840880 | 0.62 | TGFBR1 (0.45) | TP53MAPTNPC1RAB9A | |
| SCHEMBL14849633 | 0.61 | MAPK14 (0.58) | — | |
| SCHEMBL14840519 | 0.60 | PRCP (0.46) | TP53NPC1RAB9A | |
| SCHEMBL1002033 | 0.59 | PTGS2 (0.58) | TP53MAPT | |
| SCHEMBL7944018 | 0.59 | MAPK13 (0.52) | TP53MAPTNPC1RAB9A | |
| SCHEMBL1000153 | 0.58 | FAAH (0.60) | TP53MAPTNPC1RAB9A | |
| SCHEMBL1002400 | 0.58 | TP53 (0.46) | TP53MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094209-A1 | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF PAIN AND OTHER INDICATONS | MERCK SHARP & DOHME CORP. (US) | 2011-08-04 | — | — | WO | disclosed |