Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955432 | 0.78 | MAPT (0.46) | ALDH1A1MAPTGLAMETBRD4 | |
| SCHEMBL6967041 | 0.75 | ALDH1A1 (0.45) | ALDH1A1MAPTGLAIDH1DRD4 | |
| SCHEMBL6967044 | 0.74 | MAPT (0.45) | ALDH1A1MAPTGLAIDH1DRD4 | |
| SCHEMBL6964408 | 0.73 | ALDH1A1 (0.43) | ALDH1A1MAPTGLAIDH1SLC6A2 | |
| SCHEMBL6972441 | 0.72 | ALDH1A1 (0.43) | ALDH1A1MAPTGLAIDH1DRD4 | |
| SCHEMBL6965452 | 0.71 | SOS1 (0.41) | ALDH1A1MAPTCYP11B2CREBBP | |
| SCHEMBL6968547 | 0.71 | ALDH1A1 (0.42) | ALDH1A1MAPTGLAIDH1SLC6A2 | |
| SCHEMBL6971588 | 0.71 | PDE9A (0.47) | ALDH1A1MAPTGLAMET | |
| SCHEMBL6969069 | 0.70 | ALDH1A1 (0.41) | ALDH1A1MAPTDRD4DRD3 | |
| SCHEMBL6973145 | 0.69 | ALDH1A1 (0.40) | ALDH1A1MAPTGLAIDH1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |