Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | VNN1 | O95497 | 4/20 | 0.42 |
| ▸ | PDE9A | O76083 | 3/20 | 0.42 |
| ▸ | MET | P08581 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971588 | 0.86 | PDE9A (0.47) | MAPTALDH1A1VNN1PDE9AMET | |
| SCHEMBL6962751 | 0.81 | HTR2C (0.43) | VNN1METKCNH2CYP1A2CYP3A4 | |
| SCHEMBL6965452 | 0.80 | SOS1 (0.41) | MAPTALDH1A1VNN1PDE9AJAK2 | |
| SCHEMBL6959349 | 0.78 | VNN1 (0.47) | ALDH1A1VNN1METKCNH2CYP1A2 | |
| SCHEMBL6955428 | 0.78 | ALDH1A1 (0.47) | MAPTALDH1A1METBRD4TSHR | |
| SCHEMBL6960353 | 0.77 | ALDH1A1 (0.41) | MAPTALDH1A1VNN1METKCNH2 | |
| SCHEMBL6969069 | 0.77 | ALDH1A1 (0.41) | MAPTALDH1A1 | |
| SCHEMBL6967041 | 0.74 | ALDH1A1 (0.45) | MAPTALDH1A1PDE9AMETGLA | |
| SCHEMBL6967044 | 0.73 | MAPT (0.45) | MAPTALDH1A1PDE9ATSHRGLA | |
| SCHEMBL6964408 | 0.72 | ALDH1A1 (0.43) | MAPTALDH1A1VNN1GLAJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |