Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 5/20 | 0.47 |
| ▸ | ACP1 | P24666 | 1/20 | 0.45 |
| ▸ | VNN1 | O95497 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955432 | 0.86 | MAPT (0.46) | PDE9AACP1VNN1ALDH1A1MAPT | |
| SCHEMBL6960353 | 0.73 | ALDH1A1 (0.41) | ACP1VNN1ALDH1A1MAPTMET | |
| SCHEMBL6971447 | 0.71 | SLC6A2 (0.41) | VNN1ALDH1A1MAPT | |
| SCHEMBL6955428 | 0.71 | ALDH1A1 (0.47) | ALDH1A1MAPTMETGLA | |
| SCHEMBL6962751 | 0.69 | HTR2C (0.43) | ACP1VNN1METKCNH2KDM4E | |
| SCHEMBL6959349 | 0.69 | VNN1 (0.47) | ACP1VNN1ALDH1A1METKCNH2 | |
| SCHEMBL6965452 | 0.68 | SOS1 (0.41) | PDE9AVNN1ALDH1A1MAPTJAK2 | |
| SCHEMBL6959537 | 0.68 | VNN1 (0.48) | ACP1VNN1ALDH1A1METKCNH2 | |
| SCHEMBL6960930 | 0.67 | VNN1 (0.47) | ACP1VNN1ALDH1A1MAPTMET | |
| SCHEMBL22791987 | 0.66 | VNN1 (0.49) | ACP1VNN1ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |