⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19345044 | 0.81 | ALDH1A1 (0.35) | — | |
| SCHEMBL6965759 | 0.72 | ALDH1A1 (0.32) | — | |
| SCHEMBL6964285 | 0.70 | MGAM (0.31) | — | |
| SCHEMBL20115387 | 0.68 | ALDH1A1 (0.36) | — | |
| SCHEMBL6955652 | 0.67 | — | — | |
| SCHEMBL4145027 | 0.66 | TDP1 (0.35) | — | |
| SCHEMBL19484895 | 0.64 | — | — | |
| SCHEMBL2757994 | 0.64 | TDP1 (0.40) | — | |
| SCHEMBL9520463 | 0.64 | TDP1 (0.33) | — | |
| SCHEMBL25907780 | 0.62 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340751-B1 | REACTION OF IMIDAZOLONE WITH AMIDE AND MAGNESIUM COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-01-22 | — | — | US | claimed |
| EP-0974582-B1 | Process for the preparation of 4-substituted azetidinone derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 2003-02-12 | — | — | EP | disclosed |
| US-6340751-B1 | REACTION OF IMIDAZOLONE WITH AMIDE AND MAGNESIUM COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-0573667-B1 | PROCESS FOR PRODUCING 4-SUBSTITUTED AZETIDINONE DERIVATIVE | NIPPON SODA CO (JP) | 2001-06-13 | — | — | EP | disclosed |
| EP-0974582-A1 | Process for the preparation of 4-substituted azetidinone derivatives | Takasago International Corporation (JP) | 2000-01-26 | — | — | EP | disclosed |
| US-5731431-A | Process for preparing 4-substituted azetidinone derivatives | NIPPON SODA CO., LTD. (JP) | 1998-03-24 | — | — | US | disclosed |
| EP-0573667-A1 | PROCESS FOR PRODUCING 4-SUBSTITUTED AZETIDINONE DERIVATIVE | NIPPON SODA CO., LTD. (JP) | 1993-12-15 | — | — | EP | disclosed |