SCHEMBL6964285

SCHEMBL6964285

CCC(=O)N(C(=O)OC)C(C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
SOAT1 P35610 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19345044 0.81 ALDH1A1 (0.35) SOAT1
SCHEMBL6955652 0.79
SCHEMBL27783282 0.75 ALDH1A1 (0.30)
SCHEMBL20115387 0.72 ALDH1A1 (0.36) GAA
SCHEMBL6964767 0.70 MGAM (0.35) MGAMGAASIMGAM2SOAT1
SCHEMBL27688902 0.70 TAS2R38 (0.30)
SCHEMBL6955650 0.70
SCHEMBL305960 0.68 TSHR (0.31)
SCHEMBL27995532 0.68 ALOX15 (0.33) MGAMGAASIMGAM2SOAT1
SCHEMBL4145027 0.66 TDP1 (0.35) SOAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6340751-B1 REACTION OF IMIDAZOLONE WITH AMIDE AND MAGNESIUM COMPOUND TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-01-22 US claimed
EP-0974582-B1 Process for the preparation of 4-substituted azetidinone derivatives TAKASAGO PERFUMERY CO LTD (JP) 2003-02-12 EP disclosed
US-6340751-B1 REACTION OF IMIDAZOLONE WITH AMIDE AND MAGNESIUM COMPOUND TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-01-22 US disclosed
EP-0974582-A1 Process for the preparation of 4-substituted azetidinone derivatives Takasago International Corporation (JP) 2000-01-26 EP disclosed