Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | BTK | Q06187 | 2/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.33 |
| ▸ | TRPC3 | Q13507 | 2/20 | 0.32 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | MARK3 | P27448 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955983 | 1.00 | EGFR (0.39) | EGFRBTKJAK3KCNH3TRPC3 | |
| SCHEMBL6962723 | 0.92 | LMNA (0.33) | EGFRBTKKCNH3THRBKMT2A | |
| SCHEMBL6958341 | 0.92 | LMNA (0.33) | EGFRBTKKCNH3THRBKMT2A | |
| SCHEMBL6967711 | 0.90 | TRPC3 (0.37) | KCNH3TRPC3TRPC6THRBTRPM8 | |
| SCHEMBL6967410 | 0.88 | KCNH3 (0.34) | KCNH3TRPC3TRPC6THRBTRPM8 | |
| SCHEMBL6967941 | 0.88 | TRPC3 (0.34) | KCNH3TRPC3TRPC6THRBTRPM8 | |
| SCHEMBL6963630 | 0.88 | GAA (0.36) | KCNH3TRPC3TRPC6THRBTRPM8 | |
| SCHEMBL6963603 | 0.88 | KCNH3 (0.36) | KCNH3THRBKMT2AALDH1A1MEN1 | |
| SCHEMBL6954449 | 0.87 | NOTUM (0.36) | KCNH3TRPC3TRPC6THRBKMT2A | |
| SCHEMBL6962206 | 0.86 | MAPT (0.36) | THRBKMT2AJAK2JAK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6352993-B1 | ANTIULCER AGENTS | YUHAN CORPORATION (KR) | 2002-03-05 | — | — | US | disclosed |
| EP-1015444-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION, LTD. (KR) | 2000-07-05 | — | — | EP | disclosed |
| WO-1998043968-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 1998-10-08 | — | — | WO | disclosed |