Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955139 | 0.79 | MAOA (0.39) | KDM1ASLC6A4SLC6A3SLC6A2TSHR | |
| SCHEMBL5698966 | 0.72 | KDM1A (0.51) | KDM1AHCAR3HCAR2SLC6A4SLC6A3 | |
| SCHEMBL5698913 | 0.72 | KDM1A (0.51) | KDM1AHCAR3HCAR2SLC6A4SLC6A3 | |
| SCHEMBL10193786 | 0.72 | KDM1A (0.54) | KDM1AHCAR3HCAR2SLC6A4SLC6A3 | |
| SCHEMBL6961836 | 0.71 | CHRNA1 (0.46) | KDM1AHCAR2SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL13733250 | 0.70 | HCAR3 (0.53) | KDM1AHCAR3HCAR2CCR2LMNA | |
| SCHEMBL5728531 | 0.69 | TACR1 (0.49) | KDM1ASLC6A4SLC6A3SLC6A2CCR2 | |
| SCHEMBL30096889 | 0.68 | KDM1A (0.46) | KDM1AHCAR3HCAR2SLC6A4SLC6A3 | |
| SCHEMBL715748 | 0.67 | LMNA (0.47) | KDM1AHCAR3HCAR2ARCCR2 | |
| SCHEMBL377317 | 0.67 | LMNA (0.47) | KDM1AHCAR3HCAR2ARCCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |