Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 11/20 | 0.35 |
| ▸ | HTR2A | P28223 | 10/20 | 0.35 |
| ▸ | HTR2B | P41595 | 6/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | HTR1D | P28221 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | EED | O75530 | 1/20 | 0.32 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.32 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6955982 | 0.98 | HTR2C (0.35) | HTR2CHTR2AHTR2BHTR1AHTR1D | |
| SCHEMBL21224389 | 0.83 | HTR2C (0.36) | HTR2CHTR2AHTR2BHTR1AHTR1D | |
| SCHEMBL29421603 | 0.83 | HTR2C (0.36) | HTR2CHTR2AHTR2BHTR1AHTR1D | |
| SCHEMBL6955732 | 0.83 | EED (0.41) | EEDSUZ12EZH2 | |
| SCHEMBL6949055 | 0.81 | HTR2C (0.35) | HTR2CHTR2AHTR2BHTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL6956077 | 0.81 | EED (0.40) | HTR2CHTR2AEEDSUZ12EZH2 | |
| Hydrochloric Acid SCHEMBL6948371 | 0.80 | HTR2C (0.35) | HTR2CHTR2AHTR2BHTR1AHTR1D | |
| SCHEMBL6956175 | 0.79 | MTNR1B (0.37) | — | |
| Cyclopropane SCHEMBL6948950 | 0.76 | MTNR1A (0.39) | — | |
| SCHEMBL6953856 | 0.76 | MTNR1A (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901483-B1 | BENZOFURANS AND BENZOPYRANS AS CHRONOBIOLOGICAL AGENTS | GLAXO GROUP LTD (GB) | 2003-07-09 | — | — | EP | disclosed |
| US-5981572-A | Benzofurans and benzopyrans as chronobiological agents | GLAXO WELLCOME INC. (US) | 1999-11-09 | — | — | US | disclosed |