Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 11/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 10/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.34 |
| ▸ | SLC9A5 | Q14940 | 1/20 | 0.33 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955724 | 0.82 | EED (0.42) | — | |
| SCHEMBL6955159 | 0.82 | MTNR1B (0.42) | MTNR1BMTNR1ASLC9A1TSHRMAP3K14 | |
| SCHEMBL18301929 | 0.79 | AKR1B1 (0.47) | MTNR1BMTNR1AFABP4TSHR | |
| SCHEMBL6956181 | 0.79 | HTR2C (0.35) | — | |
| SCHEMBL21224389 | 0.78 | HTR2C (0.36) | — | |
| SCHEMBL29421603 | 0.78 | HTR2C (0.36) | — | |
| Hydrochloric Acid SCHEMBL6955982 | 0.78 | HTR2C (0.35) | — | |
| SCHEMBL7081173 | 0.77 | CA12 (0.33) | — | |
| SCHEMBL6953856 | 0.76 | MTNR1A (0.52) | MTNR1BMTNR1A | |
| Cyclopropane SCHEMBL6948950 | 0.76 | MTNR1A (0.39) | MTNR1BMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901483-B1 | BENZOFURANS AND BENZOPYRANS AS CHRONOBIOLOGICAL AGENTS | GLAXO GROUP LTD (GB) | 2003-07-09 | — | — | EP | disclosed |
| US-5981572-A | Benzofurans and benzopyrans as chronobiological agents | GLAXO WELLCOME INC. (US) | 1999-11-09 | — | — | US | disclosed |