Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 12/20 | 0.68 |
| ▸ | MMP3 | P08254 | 10/20 | 0.68 |
| ▸ | MMP9 | P14780 | 8/20 | 0.68 |
| ▸ | MMP1 | P03956 | 6/20 | 0.68 |
| ▸ | MMP14 | P50281 | 2/20 | 0.68 |
| ▸ | MMP13 | P45452 | 7/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 6/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | ADAM10 | O14672 | 2/20 | 0.32 |
| ▸ | WNT1 | P04628 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964678 | 0.92 | MMP2 (0.67) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6964593 | 0.92 | MMP2 (0.67) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6971907 | 0.92 | MMP2 (0.65) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6968614 | 0.92 | MMP2 (0.64) | MMP2MMP3MMP9MMP1MMP14 | |
| Hydrochloric Acid SCHEMBL6965337 | 0.91 | MMP2 (0.66) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6434330 | 0.91 | MMP2 (0.63) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6435951 | 0.90 | MMP3 (0.69) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6435947 | 0.90 | MMP3 (0.69) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6435956 | 0.90 | MMP3 (0.69) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6959147 | 0.90 | MMP2 (0.66) | MMP2MMP3MMP9MMP1MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181017-B1 | METALLOPROTEASE INHIBITORS | PFIZER LTD (GB) | 2003-04-16 | — | — | EP | claimed |