Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | DHODH | Q02127 | 1/20 | 0.56 |
| ▸ | CSNK1D | P48730 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6958936 | 0.88 | LMNA (0.57) | NPC1RAB9AMEN1KMT2ACSNK1D | |
| SCHEMBL8893941 | 0.86 | MAPT (0.65) | NPC1RAB9AMEN1KMT2ACSNK1D | |
| SCHEMBL6964080 | 0.86 | SCD (0.54) | NPC1RAB9AMEN1KMT2ACSNK1D | |
| SCHEMBL6951823 | 0.84 | RAB9A (0.64) | NPC1RAB9AMEN1KMT2ACSNK1D | |
| SCHEMBL6963623 | 0.84 | CSNK1D (0.66) | NPC1RAB9AMEN1KMT2ADHODH | |
| SCHEMBL6963867 | 0.84 | ALDH1A1 (0.54) | NPC1RAB9AMEN1KMT2ACSNK1D | |
| SCHEMBL6952703 | 0.84 | NPC1 (0.58) | NPC1RAB9AMEN1KMT2ADHODH | |
| SCHEMBL6963999 | 0.84 | NPC1 (0.55) | NPC1RAB9AMEN1KMT2ADHODH | |
| SCHEMBL6955046 | 0.84 | ALDH1A1 (0.50) | NPC1RAB9AMEN1KMT2ACSNK1D | |
| SCHEMBL6955478 | 0.82 | NPC1 (0.47) | NPC1RAB9AMEN1KMT2ADHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540143-B1 | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 2003-02-05 | — | — | EP | disclosed |
| US-5714503-A | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 1998-02-03 | — | — | US | disclosed |
| US-5658907-A | THIOUREA VIRICIDES | MEDIVIR A/B (SE) | 1997-08-19 | — | — | US | disclosed |
| US-5593993-A | VIRICIDES FOR HTLV TREATMENT OF AIDS | MEDIVIR AB (SE) | 1997-01-14 | — | — | US | disclosed |
| EP-0540143-A2 | Compounds and methods for inhibition of HIV and related viruses | Medivir Aktiebolag (SE) | 1993-05-05 | — | — | EP | disclosed |
| WO-1993003022-A1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1993-02-18 | — | — | WO | disclosed |