Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | SCD | O00767 | 3/20 | 0.60 |
| ▸ | BCHE | P06276 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 1/20 | 0.60 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.57 |
| ▸ | RELA | Q04206 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | MPI | P34949 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891868 | 0.90 | MAPT (0.81) | MAPTALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL6958936 | 0.87 | LMNA (0.57) | MAPTALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL6956229 | 0.86 | NPC1 (0.56) | MAPTALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL6951823 | 0.83 | RAB9A (0.64) | MAPTALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL6958863 | 0.82 | ALDH1A1 (0.53) | MAPTALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL10807219 | 0.82 | NPC1 (0.74) | MAPTALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL2791137 | 0.81 | NPC1 (0.65) | MAPTALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL16553901 | 0.81 | MAPT (0.76) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6963999 | 0.81 | NPC1 (0.55) | MAPTALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL6952703 | 0.81 | NPC1 (0.58) | MAPTALDH1A1HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593993-A | VIRICIDES FOR HTLV TREATMENT OF AIDS | MEDIVIR AB (SE) | 1997-01-14 | — | — | US | disclosed |