Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 19/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 18/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 11/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6671775 | 0.72 | PTGS2 (0.71) | PTGS2PTGS1ALOX5 | |
| SCHEMBL8888897 | 0.70 | PTGS2 (0.56) | PTGS2PTGS1ALOX5 | |
| Hydrochloric Acid SCHEMBL8866553 | 0.70 | PTGS2 (0.74) | PTGS2PTGS1ALOX5 | |
| Hydrochloric Acid SCHEMBL8865521 | 0.69 | ALOX5 (0.62) | PTGS2PTGS1ALOX5 | |
| SCHEMBL7569163 | 0.68 | RXRA (0.57) | PTGS2PTGS1ALOX5 | |
| SCHEMBL15726927 | 0.67 | PTGS2 (0.57) | PTGS2PTGS1ALOX5 | |
| SCHEMBL4614280 | 0.67 | PTGS2 (0.81) | PTGS2PTGS1ALOX5 | |
| SCHEMBL7789068 | 0.67 | PTGS2 (0.74) | PTGS2PTGS1ALOX5 | |
| SCHEMBL7564450 | 0.66 | PTGS2 (0.67) | PTGS2PTGS1ALOX5 | |
| SCHEMBL6669568 | 0.66 | PTGS2 (0.55) | PTGS2PTGS1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0904270-B1 | DIHYDROBENZOFURAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | UNIV VANDERBILT (US) | 2003-09-24 | — | — | EP | disclosed |