Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 16/20 | 0.46 |
| ▸ | TACR2 | P21452 | 14/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6957829 | 0.91 | TACR3 (0.54) | TACR3TACR2OPRM1KCNH2TRPV4 | |
| Hydrochloric Acid SCHEMBL6958335 | 0.90 | TACR3 (0.53) | TACR3TACR2OPRM1KCNH2TRPV4 | |
| SCHEMBL6953405 | 0.86 | TACR3 (0.41) | TACR3TACR2OPRM1KCNH2TRPV4 | |
| SCHEMBL6626342 | 0.83 | TRPV4 (0.50) | TACR3TACR2OPRM1KCNH2TRPV4 | |
| Bromide SCHEMBL6948962 | 0.83 | TACR3 (0.39) | TACR3TACR2OPRM1KCNH2TRPV4 | |
| SCHEMBL6959275 | 0.82 | TACR3 (0.55) | TACR3TACR2OPRM1KCNH2TRPV4 | |
| SCHEMBL6627408 | 0.80 | TACR3 (0.43) | TACR3TACR2OPRM1KCNH2TRPV4 | |
| SCHEMBL5945353 | 0.78 | TRPV4 (0.63) | TACR3TACR2OPRM1KCNH2TRPV4 | |
| Hydrochloric Acid SCHEMBL6953706 | 0.75 | TACR3 (0.41) | TACR3TACR2OPRM1KCNH2TRPV4 | |
| SCHEMBL6201760 | 0.74 | TACR3 (0.62) | TACR3TACR2OPRM1KCNH2TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339691-A1 | NOVEL COMPOUNDS | GlaxoSmithKline S.p.A. (IT) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002044154-A1 | NOVEL COMPOUNDS | GLAXOSMITHKLINE SPA (IT) | 2002-06-06 | — | — | WO | disclosed |